What does glucose AUC mean?

The glucose area under the curve (AUC), which is an index of whole glucose excursion after glucose loading, has been widely used for calculating the glycemic index [5] and for evaluating the efficacy of medications for postprandial hyperglycemia [6].

Is GCT same as OGTT?

Aims: Pregnant women commonly undergo screening for gestational diabetes mellitus (GDM) using a 50-g glucose challenge test (GCT), followed by a diagnostic oral glucose tolerance test (OGTT) in those women in whom the GCT is abnormal.

What is the difference between AUC and iAUC?

In conclusion, in both healthy and type 2 diabetic subjects total AUC is highly correlated to fasting TG, whereas iAUC more accurately describes the TG response to an oral fat load. The 3-point test seems less suitable for the determination of postprandial response in both healthy and type 2 diabetic subjects.

Is GCT same as GTT?

BACKGROUND AND AIM: GCT (GLUCOSE CHALLENGE TEST) WITH 50 GRAMS OF GLUCOSE IN NON-FASTING BLOOD GLUCOSE METER IN ONE-HOUR IS TEST OF PREVIOUS YEARS AND GTT (GLUCOSE TOLERANCE TEST) WITH MEASUREMENT OF FASTING GLUCOSE, AND GLUCOSE ONE AND TWO HOURS AFTER EAT 100 G OF GLUCOSE IS A NEW TEST, THE WORLD HEALTH ORGANIZATION …

What does AUC stand for in medical terms?

area under the curve. A representation of total drug exposure. The area-under-the-curve is a function of (1) the length of time the drug is present, and (2) the concentration of the drug in blood plasma.

What is insulin AUC?

The Area Under the Curve (AUC) is derived from the Oral Glucose Tolerance Test (OGTT) which is widely used to diagnose the Impaired Glucose Tolerance (IGT) in the clinic. Due to the variations in baseline blood glucose, the incremental Area Under Curve (iAUC) is developed.

What is the normal range of OGTT in pregnancy?

A normal fasting blood glucose level is lower than 95 mg/dL (5.3 mmol/L). One hour after drinking the glucose solution, a normal blood glucose level is lower than 180 mg/dL (10 mmol/L). Two hours after drinking the glucose solution, a normal blood glucose level is lower than 155 mg/dL (8.6 mmol/L).

What is the normal range for Ogtt?

gtt normal value The OGTT normal range for after 2 hour test results is between 140 – 199 mg/dL for pre diabetes, 200 mg/dL or greater for diabetes and greater than 153 mg/dL for gestational diabetes.

Is GTT necessary in pregnancy?

Doctors recommend having a glucose test for gestational diabetes, but it’s not mandatory. Here’s what you need to know to make an informed choice. It’s an appointment on the calendar most pregnant women dread: the glucose test (or oral glucose screening), usually scheduled around week 26 to week 28 of pregnancy.

What means AUC?

Area under the ROC Curve
AUC stands for “Area under the ROC Curve.” That is, AUC measures the entire two-dimensional area underneath the entire ROC curve (think integral calculus) from (0,0) to (1,1). Figure 5. AUC (Area under the ROC Curve). AUC provides an aggregate measure of performance across all possible classification thresholds.

What is the AUC of the OGTT curve?

As shown in the curve in Figure 1, the AUC of the time-blood glucose curve of the OGTT approximately equals the areas of two trapezoids as follows: (0 h blood glucose + 1 h blood glucose) × 1/2 + (1 h blood glucose + 2 h blood glucose) × 1/2, which equals the following: 1 h blood glucose + (0 h blood glucose + 2 h blood glucose)/2.

What is the area under the curve ( AUC ) of oral glucose tolerance test?

Objective: We adopted the area under the curve (AUC) of oral glucose tolerance test (OGTT) as a measure method of the severity of maternal hyperglycemia and investigated its relationship with adverse perinatal outcomes among women with and without gestational diabetes mellitus (GDM).

How is OGTT used to compare A1C to OGTT?

Comparison of the two groups was performed with χ 2, Mann-Whitney U, and t tests. The χ 2 test was used to determine an association between A1C and OGTT. Receiver operating characteristic (ROC) curves were generated, and the area under the ROC curve (AUC-ROC) was used to determine the performance of predictors for prediabetes.

What is the shape of the glucose curve during OGTT?

CONCLUSIONS —We conclude that the plasma glucose shape during an OGTT depends on glucose tolerance and sex. In addition, genetic factors seem to play a role. The shape index may be a useful metabolic screening parameter in epidemiological and genetic association studies.