What does fundic gland polyp mean?

Fundic gland polyps are the most common stomach polyp. They occur in the fundus, or the upper portion of the stomach. When they are found during an endoscopy, there are usually several of them, and they appear as small, smooth flat bumps. These polyps rarely develop into cancer.

Can fundic gland polyps turn into cancer?

Familial adenomatous polyposis. This rare, inherited syndrome causes certain cells on the stomach’s inner lining to form a specific type of polyp called fundic gland polyps. When associated with this syndrome, fundic gland polyps are removed because they can become cancerous.

Can fundic gland polyps go away?

Fundic gland polyps occur frequently in patients with familial adenomatous polyposis (FAP) but can also occur sporadically. These lesions are not premalignant and can change spontaneously in size and number and occasionally disappear.

How often are Fundic polyps cancerous?

Familial Adenomatous Polyposis and Fundic Gland Polyps The overall incidence of the mutation is between 1 in 10,000 and 1 in 15,000 births. By age 35 years, 95% of persons with FAP have polyps (>100 adenomas). The mean age of colon cancer in untreated persons is 39 years (range, 34-43 years).

Are PPI induced fundic gland polyps dangerous?

Fundic gland polyps (FGPs) are generally considered benign. Proton-pump inhibitors (PPIs) are used worldwide as first-line therapy for gastroesophageal reflux disease and nonsteroidal anti-inflammatory drug-induced ulcer treatment. Long-term use of PPIs increases the risk of FGP development .

What is fundic gastric mucosa?

Gastric mucosa. (1) Mucoid cells secrete gastric mucus and are common to all types of gastric glands. Mucoid cells are the main cell type found in the gastric glands in the cardiac and pyloric areas of the stomach. The necks of the glands in the body and fundic parts of the stomach are lined with mucoid cells.

What causes stomach polyps?

Stomach polyps form in response to damage to your stomach lining. The most common causes of stomach polyps are: Chronic stomach inflammation. Also known as gastritis, this condition can cause the formation of hyperplastic polyps and adenomas.

What is a polyp in the antrum?

Adenomatous polyps. Adenomatous polyps are the most common neoplastic polyp and are found in the antrum portion of the stomach (near the bottom). They are usually the beginning of stomach cancer. They may also suggest an increased risk of cancer within the intestines or elsewhere in the body.