What does it mean when a lesion is enhancing?

Therefore, an enhancing lesion is a lesion that assumes contrast medium. In some cases this contrast-enhancing lesion may be acute (e.g. an acute multiple sclerosis lesion), but in other cases an enhancement may be even related to non-acute findings (e.g. vascular malformation)

What is peripheral enhancement?

Regions of interest were processed by a parallel thinning algorithm to define central and peripheral subregions of lesions. Peripheral enhancement was quantified at every time point of the dynamic sequence as a signal difference-to-noise ratio.

What does Leptomeningeal mean?

Leptomeningeal: Having to do with the leptomeninges, the two innermost layers of tissues that cover the brain and spinal cord. Leptomeningeal metastasis refers to cancer that has spread from the original (primary) tumor to the leptomeninges.

What causes meningeal enhancement?

Recognized causes of iatrogenic meningeal enhancement after LP include traumatic LPs and intracranial hypotension from CSF leak. Both such causes are easily discerned in clinical practice.

What does Mild parenchymal enhancement mean?

Background parenchymal enhancement (BPE) is defined as the initial enhancement of the normal breast tissue in the standardized dynamic contrast-enhanced magnetic resonance imaging (MRI). BPE is categorized as minimal, mild, moderate, and marked according to the Breast Imaging Reporting and Data System (BI-RADS) [1–3].

What does enhancement on CT scan mean?

Contrast enhancement is a ubiquitous term in radiology and can be used in three ways. Firstly, it may refer to any method of exaggerating the visible difference between adjacent structures on imaging by administering contrast media/agents. This includes differentiating between normal structures.

What does enhancement mean on MRI?

‘Enhancement’ refers to a process by which lesions revealed on a breast MRI image increases in contrast at a specific rate over a given short-time interval, which indicates increased vascularity to the area.

What is a rim enhancing collection?

A ring-enhancing lesion is an abnormal radiologic sign on MRI or CT scans obtained using radiocontrast. On the image, there is an area of decreased density (see radiodensity) surrounded by a bright rim from concentration of the enhancing contrast dye.

What does enhancement on MRI mean?

What causes parenchymal enhancement?

Background parenchymal enhancement (BPE) on breast MRI is linked to estrogen levels and varies among women. BPE is a dynamic process and can change over time, diminishing by women age. Postmenopausal women, even without any lesions on the breast, should be followed up closely if they have high-grade BPE.

What is the term for leptomeningeal enhancement 3?

Terminology. The enhancement of the brain surface is known as pial or pial-arachnoid enhancement and often referred to as leptomeningeal enhancement 3. Conversely, as the thin arachnoid membrane is attached to the inner surface of the dura mater, the pachymeningeal pattern of enhancement can also be described as a dura-arachnoid enhancement 3.

How is diffuse leptomeningeal enhanced on a MRI?

In 1995 Ohta et al1 reported diffuse leptomeningeal enhancement on postcontrast T1 weighted MRI in children with moyamoya disease and named these finding the “ivy-sign”, because it resembles ivy creeping on stones. The ivy-sign can be found on fluid attenuation inversion recovery (FLAIR) images, as well as on contrast enhanced MRI. 2,3

How is leptomeningeal disease different from brain cancer?

Leptomeningeal Disease 1 Anatomy. Unlike the spread of cancer to the brain itself (brain metastases), leptomeningeal metastases involve the spread of cancer cells to the cerebrospinal fluid that bathes the brain and spinal 2 Cancers That May Lead to Leptomeningeal Metastases. 3 Incidence.

Where does leptomeningeal disease settle in the body?

Leptomeningeal Disease. This liquid circulates nutrients and chemicals to the brain and spinal cord. Once cancer cells are in the CSF, they settle in a spot in the brain and/or spinal cord and grow. We call this condition neoplastic meningitis, carcinomatous meningitis, lymphomatous meningitis, and leukemic meningitis.