Do ACE inhibitors cause leg swelling?

Angiotensin-converting enzyme (ACE) inhibitors and angiotensin-receptor blockers (ARBs) are rarely associated with peripheral edema. If peripheral edema develops from the use of a calcium channel blocker (CCB), it is not on the basis of salt and water retention because this drug class is intrinsically natriuretic.

Can ACE inhibitors cause edema?

Angiotensin-converting enzyme (ACE) inhibitors are the leading cause of drug-induced angioedema in the United States because they are so widely prescribed. Patients most commonly present with swelling of the lips, tongue, or face, although another presentation is episodic abdominal pain due to intestinal angioedema.

Can lisinopril cause swollen legs?

FDA Warnings Angioedema (swelling): This drug can cause abrupt swelling of your face, arms, legs, lips, tongue, throat, and intestines. This can be fatal. Tell your doctor right away if you have swelling or abdominal pain. You’ll be taken off of this drug and possibly given medication to reduce your swelling.

Can ACE inhibitors cause muscle weakness?

Hyperkalaemia leading to muscle weakness can be caused by ACE inhibitors.

What kind of pain does ACE inhibitor induced angioedema cause?

Affected areas — ACE inhibitor-induced angioedema most commonly affects the lips, tongue, face, and upper airway. The intestine can also be involved, presenting as acute abdominal pain with diarrhea or other gastrointestinal symptoms, but this presentation may be less well recognized.

What are the side effects of ACE inhibitors?

ACE inhibitor-induced angioedema is a rare but potentially fatal adverse effect of the class of medications that inhibit angiotensin converting enzyme (ACEi). It typically presents in the first weeks after starting the ACEi as swelling of the face, lips, or tongue in the absence of itch or urticaria.

Are there any medications that can cause angioedema?

Some medications can cause angioedema. Angiotensin-converting enzyme (ACE) inhibitors, which are used to treat , are usually responsible. It’s estimated that around 1-5% of people taking ACE inhibitors will develop drug-induced angioedema.

What are the signs and symptoms of angioedema?

Unlike edema linked to heart failure or renal disease, angioedema common takes an asymmetric pattern and isn’t gravity dependent. In a multicenter study of emergency-department patients with the condition, the most common presenting signs and symptoms were shortness of breath, lip and tongue swelling, and laryngeal edema.