What is Cardene IV used for?

Cardene I.V. (nicardipine hydrochloride) is a calcium channel blocker indicated for the short-term treatment of high blood pressure (hypertension) for patients who cannot take the medication orally.

How do you titrate a Cardene drip?

Administration: Nicardipine (Cardene) 50 mg in 250 ml NS (0.2 mg/ml) starting at 5mg/hr (25 ml/hr) IV infusion. Titrate to effect by increasing the rate of administration by 2.5 mg/hr every 5 minutes to a maximum of 15 mg/hr until desired blood pressure reduction is achieved.

When do you take nicardipine IV?

Intravenous (IV) nicardipine (Cardene IV), which demonstrates a relatively rapid onset/offset of action, is used in situations requiring the rapid control of blood pressure (BP). IV nicardipine was as effective as IV nitroprusside in the short-term reduction of BP in patients with severe or postoperative hypertension.

How do you administer nicardipine IV?

Nicardipine hydrochloride injection is administered by slow continuous infusion at a CONCENTRATION OF 0.1 MG/ML. Each vial (25 mg) should be diluted with 240 mL of compatible intravenous fluid (see below), resulting in 250 mL of solution at a concentration of 0.1 mg/mL.

How often should I take a Cardene IV infusion?

IV: 5 mg/hr by slow infusion (50 mL/hr) initially; may be increased by 2.5 mg/hr every 15 minutes; not to exceed 15 mg/hr PO dose: 20 mg q8hr; equivalent IV infusion: 0.5 mg/hr PO dose: 30 mg q8hr; equivalent IV infusion: 1.2 mg/hr PO dose: 40 mg q8hr; equivalent IV infusion: 2.2 mg/hr

How many milligrams of Cardene are in a shot?

Recommended Dosing Equivalent I.V. Infusion Rate Equivalent I.V. Infusion Rate Oral Cardene Dose 20 mg in 200 mL (0.1 mg/mL) 40 mg in 200 mL (0.2 mg/mL) 20 mg q8h 0.5 mg/hr = 5 mL/hr 0.5 mg/hr = 2.5 mL/hr 30 mg q8h 1.2 mg/hr = 12 mL/hr 1.2 mg/hr = 6 mL/hr 40 mg q8h 2.2 mg/hr = 22 mL/hr 2.2 mg/hr = 11 mL/hr

How much nicardipine is in a premixed Cardene injection?

Cardene I.V. Premixed Injection is supplied as a single-use, ready-to-use, iso-osmotic solution for intravenous administration in a 200 mL GALAXY container with 20 mg (0.1 mg/mL) nicardipine hydrochloride in either dextrose or sodium chloride.

When to give titrate Cardene premixed injections?

If oral nicardipine is to be used, administer the first dose 1 hour prior to discontinuation of the infusion. Titrate Cardene I.V. Premixed Injection slowly in patients with heart failure or impaired hepatic or renal function [see Warnings and Precautions (5.2, 5.3 and 5.4)]