What does it mean if I have CIN 1?

Low-grade neoplasia (CIN 1) refers to dysplasia that involves about one-third of the thickness of the epithelium. CIN 2 refers to abnormal changes in about one-third to two-thirds of the epithelial layer. CIN 3 (the most severe form) describes a condition that affects more than two-thirds of the epithelium.

Is dyskaryosis a CIN?

The areas of changed cells are known as cervical intraepithelial neoplasia, or CIN. CIN is graded on a scale of 1 to 3. Mild (low-grade) dyskaryosis is associated with the grade CIN 1. These changes are not cancer, and in most cases do not lead to cancer in the future.

Does cin1 mean I have cancer?

CIN 1 – it’s unlikely the cells will become cancerous and they may go away on their own; no treatment is needed and you’ll be invited for a cervical screening test in 12 months to check they’ve gone. CIN 2 – there’s a moderate chance the cells will become cancerous and treatment to remove them is usually recommended.

What percentage of CIN 1 turns into cancer?

More than 90% of infections are spontaneously cleared by the immune system within one year without treatment. Approximately 60% of CIN 1 lesions regress without treatment and less than 1% progress to cancer.

How quickly does CIN1 progress?

Overall, 82.1% of the women with CIN1 regressed within 2 years, while 1.5% progressed to a high-grade lesion within 3 years.

How serious is CIN1?

It is dangerous to leave CIN-2 and CIN-3 untreated. If, over a long period, the abnormal cells spread deeper into the cervix or to other tissues or organs, the disease is called cervical cancer and will require more aggressive treatment. High-grade lesions (CIN-3) usually take many years to develop into cancer.

Should I worry about severe dyskaryosis?

A smear test or cervical screening test is used to detect abnormal cells in your cervix (the entrance to your womb). Regular screening monitors changes in the cells. About 1 out of 20 tests show mild changes called dyskaryosis*. Don’t worry – abnormal results rarely mean cancer has developed.

Is dyskaryosis serious?

A small number of women have moderate or severe changes to the cells on their cervix. This is called high-grade dyskaryosis. These changes are also pre-cancerous in nature. The majority of cases do not lead to cancer of the cervix in the future.

How bad is CIN1?

A CIN1 is associated with a risk of evolution to a CIN2 or more severe lesion that is not markedly more important than the risk associated with a LSIL/ASC-US pap smear while the colposcopy is normal or the biopsy is negative (between 8 and 13% whatever the results of the initial colposcopy) (LE 2/3).

How long does it take for HPV to become CIN1?

77.77% (91/117) of these women developed CIN1 within an estimated interval of 24 months from the recorded onset of persistent HR-HPV infection, while 22.23% (26/117) were estimated to have developed CIN1 after persistent HR-HPV infection exceeding 24 months.

Does CIN1 mean I have HPV?

CIN-1 is due to infection with HPV (human papilloma virus). Of every 10 cases of HPV infection, eight will go away without treatment within 12 months. In addition to CIN changes, other minor abnormalities are commonly seen. These often need follow-up but do not necessarily mean that precancerous changes are developing.

Can a woman have cervical cancer with CIN 3?

CIN 3 refers to severe dyskaryosis and affects the full thickness of the cervix surface. Even with this result, it is unlikely that a woman already has cervical cancer. Even with this result, it is unlikely that a woman already has cervical cancer.

Can a woman have cervical cancer if she has dyskaryosis?

Even with this result, it is unlikely that a woman already has cervical cancer. However, it is important to treat severe dyskaryosis as soon as the changes are detected. Treatment is used to remove the abnormal area so that these cells do not develop into cancer in the future.

When is dyskaryosis identified in a cervical screening sample?

Dyskaryosis is when there is an abnormality of the nucleus (central part) of a cell. When identified in a cervical screening sample, dyskaryosis is classified into three groups:

How long does it take for cervical cancer to progress to CIN?

The diagnosis of dyskaryosis is made on cytology – from a smear sample. If CIN does progress to cervical cancer, then the typical progression takes 15 years, although it may occur in 3-40. Although most cancers will progress through the stages of CIN first, some very high grade neoplasms will not present as CIN first.