When to add another 10 mg of baclofen?

You should add another 10 mg tablet after 5-7 days and then wait 5-7 more days before adding further 10 mg tablets, etc. These would be added sequentially to a three-times-per-day dosing of the baclofen as morning, noon, and evening. If you get as high as 60 mg per day in total, you should call your doctor before going any further.

How much baclofen is in a milliliter of water?

The drug is stable in solution at 37° C and compatible with CSF. Each milliliter of Baclofen Injection (Intrathecal) contains baclofen 50 mcg, 500 mcg or 2000 mcg and sodium chloride 8.8 mg in Water for Injection; pH range is 5.5-6.8. Each ampule is intended for SINGLE USE ONLY.

How long does it take to absorb baclofen?

Response and Effectiveness Baclofen is rapidly absorbed, although absorption may be reduced with higher dosages. There is a wide variation in the way individuals respond to baclofen, with some people reporting a reduction in symptoms of muscle spasm within a few hours, whereas for some others it may take several weeks. 7.

What are the effects of baclofen on the body?

Applies to baclofen: compounding powder, intrathecal solution, oral liquid, oral suspension, oral tablet Common (1% to 10%): Cardiac output decreased, hypotension, hypertension, diminished cardiovascular functions, peripheral edema Frequency not reported: Rash, sweating, contact dermatitis, skin ulcer [ Ref]

How is baclofen used as a muscle relaxer?

Baclofen is a muscle relaxer and an antispasmodic agent. Baclofen is used to treat muscle pain, spasms, and stiffness in people with multiple sclerosis or spinal cord injury or disease. Baclofen is given intrathecally (directly into the spinal cord) or orally (by mouth).

What is the molecular weight of baclofen USP?

Baclofen USP is a white to off-white, odorless or practically odorless crystalline powder, with a molecular weight of 213.66. It is slightly soluble in water, very slightly soluble in methanol, and insoluble in chloroform. Each tablet for oral administration, contains 10 mg or 20 mg Baclofen, USP.