What is Magee score?

It is a quantitative reverse transcription polymerase chain reaction based assay, used to estimate the risk of distant recurrence for patients with ER positive, lymph node negative breast cancers. It is reported as a numerical score (recurrence score or RS) ranging from 0-100.

What is a MammaPrint score?

The MammaPrint test looks at the activity of 70 genes and then calculates a recurrence score that is either low risk or high risk. If you decide to have the MammaPrint test, you and your doctor will consider a number of factors when deciding on whether to add chemotherapy to your treatment plan, including: your age.

How is Oncotype score calculated?

The original Magee equation is represented as follows: recurrence score=13.424+5. 420*(nuclear grade)+5.538*(mitotic count)−0.045*(ER H-score)−0.030*(PR H-score)+9.486*(0 for negative/equivocal and 1 for HER2 positive).

What is Ki 67 a marker for?

Ki-67 protein has been widely used as a proliferation marker for human tumor cells for decades. In recent studies, multiple molecular functions of this large protein have become better understood.

What should my Magee equation score be for breast cancer?

Cases with ME scores less than 18, or 18 to 25 and mitosis score 1, do not require Oncotype DX testing, an estimated saving of US$280,000 per 100 clinical requests.

How to contact Magee Womens Hospital Breast Cancer Program?

» Learn more about Magee-Womens Breast Cancer Program. For more information, please contact Magee-Womens Hospital by filling out a form online or calling 1-866-696-2433 (MyMagee).

What is the MES score for breast cancer?

The MEs scores in decimals were not rounded off for categorization. The remaining cases were labeled as send, that is cases with any MEs score more than 25 to less than 31 and MEs scores from 18 to 25 but mitosis score of 2 or 3.

Can a breast cancer case be excluded from Oncotype DX?

To investigate use of Magee equations (MEs) to determine which breast cancer cases can be excluded from Oncotype DX testing. A prospective value study was carried out using data from pathology reports.