Is Santyl enzymatic debridement?

Collagenase Santyl® Ointment is a sterile enzymatic debriding ointment which contains 250 collagenase units per gram of white petrolatum USP. The enzyme collagenase is derived from the fermentation by Clostridium histolyticum. It possesses the unique ability to digest collagen in necrotic tissue.

What is collagenase Santyl used for?

This product is used to help the healing of burns and skin ulcers. Collagenase is an enzyme. It works by helping to break up and remove dead skin and tissue. This effect may also help antibiotics to work better and speed up your body’s natural healing process.

Is collagenase a debriding agent?

Evidence presented demonstrates that collagenase ointment is an effective, selective, and safe wound debriding agent.

What is Autolytic debridement?

Autolytic debridement is the lysis, or breakdown, of damaged tissue at a wound site by the body’s natural defence system by enzymes that digest specific components of body tissues or cells, e.g. proteins, fibrin and collagen (Ramundo 2007).

What can collagenase santyl ointment be used for?

It selectively removes necrotic tissue without harming granulation tissue. Collagenase SANTYL Ointment is indicated for debriding chronic dermal ulcers and severely burned areas.

Where does santyl ointment get its enzyme from?

The enzyme in SANTYL Ointment is derived from fermentation by Clostridium histolyticum. This type of collagenase works differently than the natural collagenase found in the human body.

Which is the only enzymatic debrider approved by the FDA?

Collagenase SANTYL◊. About. Collagenase SANTYL Ointment is the only enzymatic debrider approved by the FDA for use in the U.S. It selectively removes necrotic tissue without harming granulation tissue. Collagenase SANTYL Ointment is indicated for debriding chronic dermal ulcers and severely burned areas.

When to stop using santyl dermal ointment?

SANTYL Ointment is indicated for debriding chronic dermal ulcers and severely burned areas. Important Safety Information. Important Safety Information:Use of SANTYL Ointment should be terminated when debridement is complete and granulation tissue is well established.

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