Guidelines

What antihypertensive is contraindicated in diabetes?

What antihypertensive is contraindicated in diabetes?

As a general rule, β-blockers should not be used as first-line treatment in patients with diabetes mellitus and hypertension due to unfavorable effect on endocrine metabolism.

Why are ACE inhibitor the medication of choice for diabetics with hypertension?

The angiotensin-converting-enzyme (ACE) inhibitors are able to slow the progression of diabetic nephropathy by reducing the glomerular hypertension that causes it.

Should every diabetic be on an ACE inhibitor?

Ideally, therefore, all diabetic patients with renal or cardiovascular disease should be treated with ACE inhibitors or ARBs.

Which antihypertensive drug has to be avoided in a diabetic patient who is taking insulin?

Both β-blockers and thiazide diuretics worsen insulin resistance and deteriorate lipoprotein metabolism.

Why are beta blockers contraindicated in diabetes?

beta-blockers can potentially increase blood glucose concentrations and antagonize the action of oral hypoglycemic drugs.

Is amlodipine good for diabetic?

Amlodipine (Pfizer Inc., New York, NY, USA) is a well-established, long-acting CCB for the treatment of hypertension, including patients with diabetes.

What is the best diuretic for a diabetic?

We conclude that Indapamide is safe and effective in lowering blood pressure and contributes to better control of blood glucose and lipid levels in diabetic and dyslipidemic patients, compared to standard diuretics.

What is the best ACE inhibitor for diabetics?

Captopril is the only FDA-approved ACE inhibitor for diabetic nephropathy although other ACE inhibitors may be as effective. Several studies demonstrated that lisinopril is effective in the reducing urinary albumin excretion in diabetes[2].

Why is lisinopril prescribed to diabetics?

In people with diabetes, lisinopril helps prevent kidney disease from progressing and reduces the amount of protein that goes unfiltered by the kidneys and ends up in urine (a.k.a. proteinuria).

How are antihypertensive drugs used to treat diabetes?

It has long been known that antihypertensive drugs may affect blood glucose in a differential manner. In particular new onset diabetes is significantly increased in association with the use of thiazides or beta-blockers, respectively, compared to placebo, whereas treatment with angiotensin-conversio …

How to control blood pressure in patients with diabetes?

Most patients with concomitant hypertension and diabetes require more than one agent to attain adequate blood pressure control. In the HOT trial,23 68 percent of patients were maintained on combination antihypertensive therapy.

Are there any medications that can help with hypertension?

Angiotensin II receptor blockers also show promise in the treatment of hypertension in diabetes. In many patients, a combination of two or more of these agents is necessary to reach blood pressure goals.

When to use beta blockers in diabetes patients?

Beta blockers should be used as part of the initial antihypertensive regimen in patients with diabetes and a history of myocardial infarction, heart failure, coronary artery disease, or stable angina.