How do diuretics cause Hypochloremia?

Hypochloremia may result from renal losses that also deplete sodium, such as osmotic dilution or use of diuretics. Hypochloremia with normal plasma sodium is observed in respiratory alkalosis, which may occur, for example, in the cases of pulmonary edema, chronic obstructive pulmonary disease, or asthma.

Does furosemide cause Hypochloremia?

As with many diuretics, it can cause dehydration and electrolyte imbalance, including loss of potassium, calcium, sodium, and magnesium. Excessive use of furosemide will most likely lead to a metabolic alkalosis due to hypochloremia and hypokalemia.

Do diuretics affect chloride levels?

Continued use of diuretics, will cause some overall sodium and chloride loss.

Can diuretics cause low chloride levels?

People with congestive heart failure retain large amounts of fluids and develop resistance to diuretics, which causes low blood chloride levels [26].

How is hypochloremia related to diuretic resistance?

Conclusions: Hypochloremia is associated with neurohormonal activation and diuretic resistance with chloride depletion as a candidate mechanism. Sodium-free chloride supplementation was associated with increases in serum chloride and changes in several cardiorenal parameters.

What causes hypochloremia and what are the side effects?

Hypochloremia, along with other electrolyte imbalances, can be caused by chemotherapy treatment. These side effects can contribute to a loss of fluids. Fluid loss through vomiting and diarrhea can lead to an electrolyte imbalance.

Which is better renal wasting or hypochloremia?

Hypochloremic versus nonhypochloremic patients exhibited renal wasting of chloride (P=0.04) and of chloride relative to sodium (P=0.01), despite better renal free water excretion (urine osmolality 343±101 mOsm/kg versus 475±136; P<0.001).

What can you do if your chloride level is low?

Your doctor may use a blood test to confirm hypochloremia. In mild cases, replenishing the chloride in your body can treat hypochloremia. This can be accomplished either by consuming more salt or through receiving IV fluids. If your low chloride levels are due to a medication or an existing condition,…