Where is the HERC2 gene?

15q13
Gene locus The full HERC2 gene is located at 15q13, encoded by 93 exons and its transcription is under the control of a CpG rich promoter. This region on chromosome 15 is susceptible to breaks during chromosomal rearrangement and there are at least 12 partial duplicates of HERC2 between 15q11–15q13.

What does the HERC2 gene do?

HERC2 (HECT And RLD Domain Containing E3 Ubiquitin Protein Ligase 2) is a Protein Coding gene. Diseases associated with HERC2 include Mental Retardation, Autosomal Recessive 38 and Skin/Hair/Eye Pigmentation, Variation In, 1. Among its related pathways are Cell Cycle Checkpoints and Metabolism of proteins.

What are genes state their location?

Genes are a section of DNA that are in charge of different functions like making proteins. Long strands of DNA with lots of genes make up chromosomes. DNA molecules are found in chromosomes. Chromosomes are located inside of the nucleus of cells.

Which gene is mutated to cause blue eyes?

Blue eye color in humans may be caused by a perfectly associated founder mutation in a regulatory element located within the HERC2 gene inhibiting OCA2 expression.

What gene causes blue eyes?

Blue Eyes. Originally, all humans had brown eyes. Some 6,000 to 10,000 years ago, a genetic mutation affecting one gene turned off the ability to produce enough melanin to color eyes brown causing blue eyes. This mutation arose in the OCA2 gene, the main gene responsible for determining eye color.

Do people with blue eyes have higher IQS?

Baby blues aren’t just a striking physical attribute anymore — sapphire peepers may actually indicate a higher level intelligence, according to more than one study.

What color eyes are the smartest?

Here are the results: People with grey eyes are perceived to be the smartest. Blue-eyed people are seen as being the most expressive. Those with green eyes are deemed adventurous. Brown eyes are perceived the most kind.