What is the use of rapid mixer granulator?

Rapid mixer granulator is widely used equipment in pharmaceutical manufacturing. It is used to mix the pharmaceutical ingredients and make the granules before compression and also called a high shear mixer. Impellers and chopper are mainly responsible for wet granulation in the rapid mixer granulator.

How do you use a rapid mixer granulator?

5.15 Open the lid & rack the material then closed the lid. Start the agitator by setting the timer in the panel. After achieving the desired specific end point (Ampere Load) given in BMR, stop the operation and open the discharge valve with the help of knob provided on the panel.

What is RMG principle?

Working principle of RMG: Rapid mixture granulator works on agitation, tumbling. The impeller is responsible for uniformly mixing wet granules and copper helps in a break or reduced particle size.

What is high shear mixer granulator?

High shear granulation is a shaping process for granulation that has been enhanced for application in the pharmaceutical industry. A binder liquid is fed to the powder particles in a closed container with blending tools and a chopper. Dense granules are formed through the liquid and solid bridges that result.

What is tip speed in RMG?

Blade Speed (tip speed), measures how far a point on the outer most edge of the disperser blade travels in a given amount of time. You may remember from early math classes that the circumference (perimeter) of a circle is equal to: Circumference = Π × D.

What is the end point of RMG?

Impeller or Motor Shaft Speed End Point in a wet granulation process is characterized by rheological properties of the wet mass such as density, viscosity etc which are in turn a function of particle size, shape and other physical properties.

How does a tumbling granulator work?

In tumbling granulators, particles are set in motion by the tumbling action caused by the balance between gravity and centrifugal forces. Tumbling equipment can also be used for coating relatively large (group D) particles. Discs and drums generally operate continuously and can be up to 4 m in diameter.

How is RMG occupancy calculated?

Calculation for RMG of 600 Lit capacity is as follows: 100% occupancy of equipment: 600 Lit × 0.5 gm/ml=300 kg.

Why is RMG capacity in liters?

It’s a design issue. The main functionality of RMG is “holding, mixing and granulating of standard volume”. You product may be cotton (lowest density) or osmium (highest density), you can process only the standard volume in your RMG. Hence its capacity is mentioned in liters.

What are the advantages of high-shear granulation *?

High-shear granulator minimizes the exposure of drug dust to workers due to reduced process dust generation. 6. Granulation endpoint is predictable while using a high-shear granulator. 7.

What is high speed granulator?

Introduction: The PerMix PDI series High Speed Mixer, also called Mixer Granulator, Wet Granulator, or High Shear Mixer Granulator, is an efficient and versatile blending machine for mixing of dry powders, or granulating with the addition of liquid binder, within a very short time and with excellent cleaning abilities.

How do you calculate tip speed?

To calculate tip speed you simply multiply the diameter of the impeller by pi (3.14159) which gives you the circumference of the impeller at the outermost tip. You then multiply by the rotational speed of the impeller (usually rpm, or rps) and this result is tip speed.

What is the purpose of a rapid Mixer granulator?

Working and Principle of Rapid Mixer Granulator (RMG) Rapid mixer granulator is used for granulation in pharmaceutical manufacturing. Impellers and choppers are responsible for uniform mixing and granule formation. Rapid mixer granulator is widely used equipment in pharmaceutical manufacturing.

Which is the best granulator for wet granulation?

Rapid Mixer Granulator (RMG) We are one of the pioneer Pharmaceutical Machinery Manufacturers from India, We manufacture Rapid Mixer Granulator which is used in Pharma Industry for Wet Granulation, it is also known as High Shear Mixer.

How big is a Riddhi rapid Mixer granulator?

Useful working capacity of upto 80% to 40% of bowl volume. Uniform granules by gentle processing. Wide range of applications. Easy scale up & Scale down between machine sizes. Bowl shape design to have no dead spaces. Riddhi Mixer Granulator’s can be offered in 10Ltrs. R&D & 25Ltr. / 50Ltr. For R&D or pilot plants.

What can you do with a High Shear Mixer granulator?

The Rapid Mixer Granulator (RMG) or High Shear Mixer Granulator produces granular products that can be used in a pharmaceutical company. Other types of the high Shear mixer can generate suspensions (gas distributed in liquid) as well as emulsions.