What is Laugier-Hunziker syndrome?

Laugier–Hunziker syndrome (LHS) is an acquired pigmentary condition affecting lips, oral mucosa and acral area, frequently associated with longitudinal melanonychia. There is neither malignant predisposition nor underlying systemic abnormality associated with LHS.

Is Laugier-Hunziker syndrome hereditary?

Laugier-Hunziker syndrome, also known as Laugier-Gerbig-Hunziker syndrome or Laugier-Hunziker-Baran syndrome or idiopathic lenticular mucocutaneous pigmentation, is a hereditary pigmentary disorder characterized by a unique expression of pigmentation over the mucosal, nail, and acral sites.

What is oral Melanosis?

Oral melanotic macule is a flat, brown, solitary or multiple mucosal discoloration of oral mucosa, which is produced by a focal increase in melanin deposition along with an increase in melanocyte count. The most commonly involved sites are lip, buccal mucosa, gingiva and palate.

How is Laugier Hunziker syndrome treated?

No treatment is required for Laugier-Hunziker syndrome. Laugier-Hunziker has no association with systemic diseases so there are few if any complications. If systemic symptoms are apparent a patient must be worked-up for another diagnosis. Cosmetically disfiguring or bothersome lesions may be treated with laser therapy.

How do you test for Peutz-Jeghers syndrome?

Children are tested for Peutz-Jeghers syndrome (PJS) by performing an upper gastroenterology (GI) endoscopy and a colonoscopy. These procedures allow the doctor to look inside the esophagus, stomach, duodenum and large intestine using separate long, flexible tubes with cameras on the end.

What is PJS medical condition?

Peutz-Jeghers syndromes (PJS) is a genetic disorder. People with PJS develop polyps and dark-colored spots that appear on various parts of the body, and are at greater risk for some types of cancer. Appointments 216.444.7000.

What color is oral melanoma?

Oral melanomas are often silent with minimal symptoms until the advanced stage. The lesions can appear as pigmented dark brown to blue-black lesions or apigmented mucosa-colored or white lesions on physical examination.

How is oral Melanosis treated?

As long as the oral melanotic macule stays stable in size, shape, and color, no treatment is needed. Nonetheless, some people want the lesion removed for cosmetic reasons. If it is appropriate, some physicians might recommend excision or, rarely, laser treatment.

How rare is Peutz Jeghers syndrome?

Peutz Jeghers syndrome is a rare disorder that affects males and females in equal numbers and can occur in any racial or ethnic group. The birth prevalence of PJS is estimated to be between 1/50,000 and 1/200,000.

How do you treat Peutz Jeghers syndrome?

Generally, polyps are treated with a procedure known as a polypectomy, which involves removing the polyps with an endoscope. If the polyps are very large, surgery may be necessary. Although there is no cure for PJS, treatment can reduce complications, such as abdominal pain, bowel obstruction, GI bleeding and cancer.

How are PJS diagnosed?

How do I know if I have oral melanoma?

Oral melanomas are often silent with minimal symptoms until the advanced stage. The lesions can appear as pigmented dark brown to blue-black lesions or apigmented mucosa-colored or white lesions on physical examination. Erythema may be present if inflammation is present.