What is L1 column packing?

According to the United States Pharmacopeia (USP), L1 column packing is defined as “octadecyl silane chemically bonded to porous silica or ceramic micro-particles, 3 to 10 m in diameter.” Some USP methods specifying an L1 column use intermediate pH, and many of these methods were done on a 10 m, 3.9 x 300 mm column.

What is L7 packing column?

L7 USP columns are described as octyl silane (C8), chemically linked to porous silica particles, 1.5 to 10 µm in diameter. Our high-quality L7 USP columns include: LiChrospher® RP-8 (5 µm).

What is L9 column?

L9 3 to 10 µm irregular, totally porous silica gel having a chemically. bonded strongly acidic cation exchanger coating (SCX). Brand. Particle Size. Type.

What is L10 column?

L10 USP columns are described as cyano groups (CN) chemically bonded to porous silica particles, 3 to 10 µm in diameter. Our portfolio includes highly reliable L10 USP columns, such as LiChrospher® CN (5 µm).

What is L3 column?

L3 USP columns are described as consisting of porous silica particles, 1.5 to 10 µm in diameter. Our L3 USP columns are produced to the highest quality standards to ensure reliable, reproducible results. A perfect example is: Purospher® STAR Si (5 µm).

What are the columns used in HPLC?

Different Types of HPLC Columns Used in Analysis

• Normal Phase Columns.
• Reverse Phase Columns.
• Ion Exchange Columns.
• Size Exclusion Columns.

What is ODS and BDS column?

ODS and BDS are two columns used for reverse-phase chromatography. The key difference between ODS and BDS column is that ODS column contains free –OH functional groups, whereas BDS column contains deactivated –OH groups. Moreover, ODS columns have high peak tailing while BDS columns are designed to reduce peak tailing.

What is C 18 column?

C18 columns are HPLC (high performance liquid chromatography) columns that use a C18 substance as the stationary phase. C18 simply means that the molecules contain 18 carbon atoms, so the other atoms in the molecule can vary, leading to significantly different substances.

Which column is more polar c8 or C18?

C18 has 18 carbon atoms while C8 has only 8 carbon atoms. C18 has a longer carbon chain, but C8 has a shorter one. C18 has higher retention while C8 has shorter retention. C18 has higher hydrophobicity, but C8 has a lower hydrophobicity….Follow Pharmaguideline.

What is hypersil BDS column?

Hypersil BDS C18 media is an excellent reversed phase material for a variety of applications and is one of the most popular packing materials available. Hypersil BDS columns are a good choice for QA/QC labs as a robust general purpose column in applications where reproducibility and long column lifetimes are required.

What kind of packing material is the L1 column?

Packing material Recommended column ; L1: Octadecyl silane chemically bonded to porous or non-porous silica or ceramic micro-particles, 1.5 to 10 μm in diameter, or a monolithic rod. C18 Silica C18M Silica C18P C18U: L3: Porous silica particles, 1.5 to 10 μm in diameter, or a monolithic silica rod. Silica 5SIL: L7

What are the columns for USP packing materials?

USP “L” Column Listings See Hamilton’s Qualifying USP “L” Columns Below USP Packing Materials Stationary Phase L1 Octadecyl silane chemically bonded to porous silica or ceramic micro-particles, 1.5 to 10 µm in diameter, or a monolithic silica rod L7

How big is a USP HPLC column L?

An essentially monomolecular layer of aminopropylsilane chemically bonded to totally porous silica gel support, 1.5 to 10 µm in diameter, or a monolithic silica rod. Irregular or spherical, totally porous silica gel having a chemically bonded, strongly acidic cation-exchange coating, 3 to 10 µm in diameter.

What kind of packing is in gimitec column L?

The packing is spherical 1.5 – 10 µm, silica or hybrid packing with a hydrophilic coating.

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