What are the function of chondrocytes?

Chondrocytes are the cells responsible for cartilage formation, and they are crucial for the process of endochondral ossification, which is useful for bone development. Also, by mimicking skeletal development chondrocytes play a critical role in fracture repair.

What is the function of chondrocytes in cartilage?

Chondrocytes in the AC proliferate and secrete extracellular matrix to maintain and sustain the cartilage. The cells themselves are separated from each other by cartilage matrix [2]. They respond to outside stimuli and tissue damage, and are also responsible for degenerative conditions, such as osteoarthritis (OA).

Does fibrocartilage have chondrocytes?

characteristics. Fibrocartilage is the tough, very strong tissue found predominantly in the intervertebral disks and at the insertions of ligaments and tendons; it is similar to other fibrous tissues but contains cartilage ground substance and chondrocytes.

What is the function of chondroblasts in cartilage?

Chondroblasts, located in the perichondrium, are cells that play an important role in the development of cartilage. By producing extracellular matrix, chondroblasts create the main component that provides structure and strength to cartilage.

What is osteoblast function?

Osteoblasts are specialized mesenchymal cells that synthesize bone matrix and coordinate the mineralization of the skeleton. The unique function of osteoblasts requires substantial amounts of energy production, particularly during states of new bone formation and remodelling.

What type of cell is chondrocyte?

What is the difference between chondrocytes and Chondroblasts?

There are two main cell types in the cartilage known as chondroblasts and chondrocytes. The key difference between chondrocytes and chondroblasts is that chondroblasts are immature cartilage cells found near the perichondrium while chondrocytes are mature cartilage cells found embedded within the extracellular matrix.

Why Perichondrium is absent in fibrocartilage?

The deeper layers of perichondrium also contains “chondrogenic” cells which become chondrocytes as they produce matrix. White fibrocartilage blends with the surrounding fibrous tissue, and therefore does not have perichondrium.

What is an example of fibrocartilage?

Specific examples of fibrocartilaginous tissues are the knee meniscus, the temporomandibular disc, and the intervertebral disc.

What is difference between osteoblast and osteoclast?

Osteoblasts are responsible for the formation of bone whereas the osteoclasts are responsible for the breakdown of the bones. The coordinated actions of these two cells are required for the formation and resorption (breakdown) of bones.

Why perichondrium is absent in fibrocartilage?

What is the function of fibrocartilage?

The fibrocartilage occurs in the pubic symphysis, menisci of the stifle joint, and the annulus fibrosis of the intervertebral discs. The fibrocartilage is often associated with the dense connective tissue and its main function is to attach bones to other bones and provide restricted mobility in the joints.

What does fibrocartilage look like?

It is a glossy blue-white in appearance and very resilient. Fibrocartilage is the tough, very strong tissue found predominantly in the intervertebral disks and at the insertions of ligaments and tendons; it is similar to other fibrous tissues but contains cartilage ground substance and chondrocytes.

What is fibrocartilage made of?

Fibrocartilage is primarily composed of type I collagen, and is located in areas like the intervertebral discs and the pubic symphysis. Note that the chondrocytes are surrounded by a matrix which helps differentiate fibrocartilage from dense connective tissue.