How much does zoledronic acid cost?

Zoledronic acid costs approximately $1,250 per dose, given once a year.

Is zoledronic acid expensive?

Zoledronic acid is more expensive than oral alendronic acid, which should be used as first-line treatment (as the generic weekly form); it is also more expensive than other oral treatments for osteoporosis once administration costs are taken into account.

What is the brand name for zoledronic acid?

you should know that zoledronic acid injection is available under the brand names Zometa and Reclast.

How long does zoledronic acid last?

Zoledronic acid is only part of a complete program of treatment that may also include diet changes and taking calcium and vitamin supplements. Follow your doctor’s instructions very closely. Your doctor will determine how long to treat you with this medicine. Zoledronic acid is often given for only 3 to 5 years.

Is zoledronic acid Safe?

Zoledronic acid had an acceptable safety profile; no adverse events were considered to be drug related. Treatment with ZA improved bone health by enhancing bone mineral density and reducing bone turnover, even in high-risk patients.

What are the benefits of zoledronic acid?

Zoledronic acid reduces the activity of the osteoclasts. This can help reduce pain and strengthen the bone. It also reduces the amount of calcium that is lost from the bones. This helps calcium levels in the blood return to normal.

Does zoledronic acid cause bone pain?

Zoledronic acid can cause bone, joint and/or muscle pain that can be severe. This can occur from 1 day to several months after starting the medication. Report these symptoms to your provider, who can advise you on strategies to relieve the pain.

What is the most common side effect of zoledronic acid?

Fever is the most common adverse effect associated with zoledronic acid infusion. Flu-like syndromes including fever, chills, bone pain, and/or arthralgias and myalgias have also occasionally been reported. These symptoms generally did not require treatment and resolved within 24 to 48 hours.

What are the side effects of zoledronic acid?

More common

• Abdominal or stomach pain.
• back pain.
• bad, unusual, or unpleasant (after) taste.
• bladder pain.
• blistering, crusting, irritation, itching, or reddening of the skin.
• bone pain.
• burning, crawling, itching, numbness, prickling, “pins and needles”, or tingling feelings.
• change in taste.

Does zoledronic acid weaken the immune system?

It still remains unclear what role zoledronic acid plays. “We know it affects the immune system and inflammation, and both of those are important in fighting infection and cardiovascular disease,” Colon-Emeric says.

Does zoledronic acid affect kidneys?

Zoledronic acid is associated with reports of renal impairment and renal failure, especially in patients with pre-existing renal dysfunction or other risk factors. Renal function should be measured before each dose, and patients should be adequately hydrated before treatment.

Is zoledronic acid nephrotoxic?

Our data confirm the previously reported risk factors for zoledronic acid-associated nephrotoxicity such as advanced cancer, multiple myeloma, preexisting renal failure, diabetes, hypertension, and concomitant use of nephrotoxic drugs.

How to find the price of zoledronic acid?

Information about drug Zoledronic Acid includes cost of the drug and the type of drug – tablet, capsule, syrup, cream, gel, ointment, liquid or injection. To view the price of the drug, click on the brand name.

Are there any side effects from taking zoledronic acid?

Check with your doctor or nurse immediately if any of the following side effects occur while taking zoledronic acid: large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs Some side effects of zoledronic acid may occur that usually do not need medical attention.

How does zoledronic acid work in osteoporosis?

Description: Zoledronic acid inhibits osteoclast activity and skeletal Ca release induced by tumours. It decreases serum Ca and phosphorus, and increases their elimination. In osteoporosis, it inhibits osteoclast-mediated resorption, thus reducing bone turnover.

How often should I take elemental zoledronic acid?

Adult: 5 mg as a single infusion over 15 min. Patients should receive elemental Ca 1,500 mg and vit D 800 IU daily particularly w/in 2 wk after admin. Patients who have relapsed: May be given an additional infusion of 5 mg after an interval of at least 1 yr from the initial dose.