How long does IV hydralazine take to work?
How long does IV hydralazine take to work?
20–25 mg of IV hydralazine hydrochloride is approximately equal to 75–100 mg of oral hydralazine hydrochloride. BP-lowering effect occurs in 20–30 minutes following oral administration, 10–30 minutes following IM administration, and 5–20 minutes following IV administration.
How fast can hydralazine be given IV?
IV Administration Use solution as quickly as possible after drawing through needle into syringe. Concentration: 20 mg/mL. Rate: Administer over at least 1 min.
When does IV hydralazine peak?
| Route | Onset | Peak |
|---|---|---|
| P.O. | 20-30 min | 1-2 hr |
| I.V. | 5-20 min | 10-80 min |
| I.M. | 10-30 min | 1 hr |
How do you give hydralazine IV?
Dilute 20 mg (1 vial of reconstituted hydralazine solution in 1 ml of water for injection) in 9 ml of 0.9% sodium chloride, to obtain 10 ml of solution containing 2 mg/ml. Administer 5 mg (2.5 ml of the diluted solution) over 2 to 4 minutes. Check BP for 20 minutes. If BP remains uncontrolled, repeat injection.
When not to give hydralazine?
Important Information. You should not use hydralazine if you have coronary artery disease, or rheumatic heart disease affecting the mitral valve. Before taking this medicine. You should not use hydralazine if you are allergic to it, or if you have: rheumatic heart disease affecting the mitral valve.
How long does before hydralazine work?
The onset of action for IV hydralazine is something like 10-20 minutes, so 10 minutes would probably work.
How long does IV hydralazine last?
IV Hydralazine ●Hydralazine is a potent vasodilator. Onset of action: upwards of 20 minutes, peak effects last for 60 minutes, duration of action is unpredictableand can persist for upwards of 8 hours.