Does Moraxella catarrhalis grow on nutrient agar?

Moraxella catarrhalis does not grow on nutrient agar without sodium chloride supplementation. Microbiol Immunol.

Is Catarrhalis gram positive?

catarrhalis is unique among gram-negative diplococci; strains of M. catarrhalis produce no reaction in enzyme substrate tests.

What media does Moraxella catarrhalis grow on?

Moraxella catarrhalis grows well on blood agar and chocolate agar, producing small, nonhemolytic, grayish-white colonies that slide across the agar surface, like a hockey puck, when pushed with a bacteriologic loop.

Which of the following is a confirmatory test for M catarrhalis?

Serum antibodies to whole-cell proteins, to lipo-oligosaccharides, and to outer-membrane antigens have proved useful in the diagnosis of M catarrhalis infection.

Can a healthy adult get m.catarrhalis?

M. catarrhalis is not frequently isolated from the oropharynx of healthy adults, but may be carried more frequently in children and older adults.

How does m.catarrhalis resistance to antibiotics work?

M. catarrhalis resistance to beta-lactam antibiotics, such as ampicillin and amoxicillin, is mediated by periplasmic lipoprotein beta-lactamases BRO-1 and BRO-2, which protect the peptidoglycan layer by hydrolyzing the beta-lactam molecules that enter the bacterial cell.

Is the USPA protein on the surface of M catarrhalis?

However, a 1994 study has identified a large protein on the surface of M. catarrhalis that may serve as a target for protective antibodies. This UspA (the designated antigen) protein is the first surface-exposed protein on M. catarrhalis that can be a target for biologically active antibodies, and therefore lead to a vaccination.

Are there any unusual pathogens other than m.catarrhalis?

Moraxella species other than M. catarrhalis are unusual pathogens in humans. Several reports have emphasized the role of other Moraxella as ocular pathogens. These bacteria cause conjunctivitis, keratitis and, rarely, endophthalmitis. 99-101 Most episodes of Moraxella keratitis have predisposing local ocular pathology.