Can butorphanol be given IM?

For pain relief the recommended initial dosage regimen of Butorphanol tartrate injection is 1 mg IV or 2 mg IM with repeated doses every three to four hours as necessary. This dosage regimen is likely to be effective for the majority of patients.

What is butorphanol tartrate injection used for?

This medication is used to treat moderate to severe pain, including pain from surgery, muscle pain, and migraine headaches. Butorphanol is an opioid pain reliever similar to morphine. It acts on certain centers in the brain to give you pain relief.

Can stadol be given IM?

In patients at full term in early labor a 1–2 mg dose of Stadol Injection IV or IM may be administered and repeated after 4 hours. Alternative analgesia should be used for pain associated with delivery or if delivery is expected to occur within 4 hours.

How do you give an IV of butorphanol?

Use in Balanced Anesthesia The usual dose of butorphanol tartrate injection is 2 mg IV shortly before induction and/or 0.5 mg to 1 mg IV in increments during anesthesia. The increment may be higher, up to 0.06 mg/kg (4 mg/70 kg), depending on previous sedative, analgesic, and hypnotic drugs administered.

How is butorphanol administered?

Pharmacodynamics. The analgesic effect of butorphanol is influenced by the route of administration. Onset of analgesia is within a few minutes for intravenous administration, within 15 minutes for intramuscular injection, and within 15 minutes for the nasal spray doses.

How strong is butorphanol?

Butorphanol is a synthetic opioid with mixed agonist/antagonist properties. It is analgesic with a potency 3 to 5 times greater than that of morphine in humans and up to 30 times greater than morphine in rats (Wixson, 1994).

Who should not take butorphanol?

Butorphanol tartrate nasal spray should not be used by patients less than 18 years old. Butorphanol has been found in the breast milk of women who are using butorphanol tartrate nasal spray. Therefore, butorphanol tartrate nasal spray should not be used by patients who are breastfeeding.

What is the antidote to stadol?

Respiratory depression noted after administration of butorphanol to humans by any route is reversed by treatment with naloxone, a specific opioid antagonist (see Treatment in OVERDOSE). Butorphanol tartrate demonstrates antitussive effects in animals at doses less than those required for analgesia.

When should I take butorphanol?

butorphanol (Rx)

1. Pain. Indicated for pain when use of opioid analgesic is appropriate.
2. Balanced Anesthesia. 2 mg IV before induction and/or 0.5-1 mg increments during anesthesia (higher dose may be required, up to 0.06 mg/kg, or 4 mg/70 kg)
3. Labor Pain.
4. Preoperative & Preanesthesia.
5. Renal & Hepatic Impairment.

Is butorphanol stronger than morphine?

Butorphanol is to 3 times more potent than morphine and has a shorter duration of action (0.5 to 3 hours), with minimal sedation (see Table 26-1). Cardiovascular and respiratory side effects are minimal compared with mu receptor agonists, and butorphanol produces antitussive and antiemetic effects.

How is butorphanol taken?

If your doctor prescribed a 2 mg dose of butorphanol tartrate nasal spray for relief of pain: Spray one spray in each nostril – two sprays equal a 2 mg dose. If instructed by your doctor, this dose of butorphanol tartrate nasal spray may be repeated every 3 to 4 hours as needed for pain relief.

How do you administer Stadol?

STADOL NS. The usual recommended dose for initial nasal administration is 1 mg (1 spray in one nostril). Adherence to this dose reduces the incidence of drowsiness and dizziness. If adequate pain relief is not achieved within 60–90 minutes, an additional 1-mg dose may be given.

What kind of spray is butorphanol tartrate 10 mg?

BUTORPHANOL TARTRATE Nasal Spray USP, 10 mg/mL CIV Rx only DESCRIPTION. Butorphanol tartrate is a synthetically derived opioid agonist-antagonist analgesic of the phenanthrene series.

When was the last update on butorphanol tartrate injection?

Last updated on Feb 1, 2020. Butorphanol tartrate injection exposes patients and other users to the risks of opioid addiction, abuse, and misuse, which can lead to overdose and death.

When to use butorphanol tartrate in balanced anesthesia?

Use in Balanced Anesthesia. The usual dose of Butorphanol tartrate injection is 2 mg IV shortly before induction and/or 0.5 to 1 mg IV in increments during anesthesia. The increment may be higher, up to 0.06 mg/kg (4 mg/70 kg), depending on previous sedative, analgesic, and hypnotic drugs administered.

How much citric acid is in butorphanol tartrate injection?

Butorphanol tartrate injection is a sterile, nonpyrogenic parenteral aqueous solution of Butorphanol tartrate for intravenous or intramuscular administration. Each milliliter (mL) contains Butorphanol tartrate 1 or 2 mg; sodium citrate, dihydrate, 6.4 mg; citric acid hydrous 3.3 mg; sodium chloride 6.4 mg.