Who invented nifedipine?

Nifedipine (initially BAY a1040, then Adalat) was developed by the German pharmaceutical company Bayer, with most initial studies being performed in the early 1970s.

What is the brand name for nifedipine?

Nifedipine is also called by various brand names, for example Adalat, Adipine, Coracten, Fortipine, Nifedipress, Tensipine and Valni. If the brand name has other letters after it (XL, LA, SR, MR, or Retard), it means that the nifedipine is released slowly and evenly throughout the day.

Are there any side effects to taking nifedipine?

Drug Warning. Nifedipine-induced peripheral edema of the lower extremities usually responds to diuretic therapy. The relatively common adverse effects reported with conventional liquid-filled (short-acting) nifedipine capsules are similar in nature to those reported with extended-release tablets of the drug.

What is the mechanism of action of nifedipine?

Chemical/Ingredient structural concept [Chemical/Ingredient] – Dihydropyridines. FDA Pharmacology Summary. Nifedipine is a Dihydropyridine Calcium Channel Blocker. The mechanism of action of nifedipine is as a Calcium Channel Antagonist. The chemical classification of nifedipine is Dihydropyridines. FDA Pharm Classes.

Which is the secondary reference material for nifedipine?

Nifedipine, Pharmaceutical Secondary Standard; Certified Reference Material 1,4-Dihydro-2,6-dimethyl-4- (2-nitrophenyl)-3,5-pyridinedicarboxylicaciddimethylester 2,6-dimethyl-4- (2nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3,5-dimethyl ester Dimethyl (4- (2-nitrophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate)

How is nifedipine used to treat angina pectoris?

(NCI04) NCI Thesaurus (NCIt) Nifedipine is a first generation calciumchannel blocker used to treat hypertension and angina pectoris. Nifedipine therapy is associated with a low rate of serum enzyme elevations and has been linked to several instances of clinically apparent acute liver injury.