Which Mucopolysaccharide maintains transparency of cornea?

In fact, the α-keratan sulfate proteoglycan appears to play a key role in the transparency of the cornea, while the major keratan sulfate proteoglycan, present in large quantities in the corneal stroma, seems to regulate the organization of collagen fibrils and is involved in wound repair of epithelial tissues of the …

Which layer is important for corneal transparency?

corneal stroma
All layers of the cornea must heal to maintain corneal transparency, but the layer that most crucial to corneal haze in response to injury is the corneal stroma.

What will happen if the corneal transparency is lost?

Transparency loss from corneal edema Corneal swelling is induced by causes such as endothelial or epithelial damage, bullous keratopathy, and Fuchs’ corneal dystrophy. In this section, the structural alterations underlying the loss of transparency in edematous corneas are discussed ( Box 1.3 ).

Why is the stroma transparent?

Stromal transparency is mainly a consequence of the remarkable degree of order in the arrangement of the collagen fibrils in the lamellæ and of fibril diameter uniformity. Light entering the cornea is scattered by each fibril.

Why does the cornea have so much transparency?

The corneal transparency is the result of uniform and regular arrangement of the corneal lamellae and corneal avascularity (the condition of having no blood vessels). Factors affecting corneal transparency:

When was the first study of corneal transparency?

About 50 years ago the basic ultrastructure had been described ( Jakus, 1962) and the principles behind corneal transparency finally elucidated ( Maurice, 1957, Hart and Farrell, 1969, Benedek, 1971) so corneal research focussed more on other areas.

Why are corneal fibrils arranged in a regular lattice?

Theory of Goldman et al. 8. • Corneal transparency is because of the uniform collagen fibrils which are arranged in a regular lattice so that scattered light is destroyed by the mutual interference.

What kind of hydration is needed for corneal transparency?

33. Corneal hydration : Normal cornea maintains itself in a state of relative dehydration (80% water content ) which is essential for corneal transparency.