What is the pKa of piperazine?

Piperazine

What is the pKa of CH3O?

Thus, leaving groups are stable when the “effective pH” is well above the pKa of the leaving group’s conjugate acid. For example, CH3O– will not be a leaving group at neutral pH (7) because the pKa of CH3OH is 17.

What is the pKa of benzene?

43
Ionization Constants of Carbon Acids

What is the pKa of chlorine?

7.5
The speciation of aqueous free chlorine above pH 5 is a well-understood equilibrium of H2O + HOCl <==> OCl- + H3O+ with a pKa of 7.5.

Is piperazine an antibiotic?

Piperazine, also called hexahydropyrazine, anthelmintic drug used in the treatment of intestinal roundworm infection in humans and domestic animals (including poultry) and against pinworm infection in humans.

Is pKa a strong acid?

Strong acids are defined by their pKa. The acid must be stronger in aqueous solution than a hydronium ion, so its pKa must be lower than that of a hydronium ion. Therefore, strong acids have a pKa of <-174. Strong acids can be organic or inorganic.

Does Low pKa mean stronger acid?

Therefore, pKa was introduced as an index to express the acidity of weak acids, where pKa is defined as follows. In addition, the smaller the pKa value, the stronger the acid. For example, the pKa value of lactic acid is about 3.8, so that means lactic acid is a stronger acid than acetic acid.

How do you convert pKa to pH?

Each dissociation has a unique Ka and pKa value. When the moles of base added equals half the total moles of acid, the weak acid and its conjugate base are in equal amounts. The ratio of CB / WA = 1 and according to the HH equation, pH = pKa + log(1) or pH = pKa.

Is a high pKa a strong acid?

In addition, the smaller the pKa value, the stronger the acid. For example, the pKa value of lactic acid is about 3.8, so that means lactic acid is a stronger acid than acetic acid.

What is the formula for N methyl piperazine?

N-METHYL PIPERAZINE PRODUCT IDENTIFICATION CAS NO. 109-01-3 EINECS NO. 203-639-5 FORMULA C5H12N2 MOL WT.

How is piperazine soluble in water and ethylene glycol?

Chemistry. Piperazine is freely soluble in water and ethylene glycol, but insoluble in diethyl ether. It is a weak base with two pKbs of 5.35 and 9.73 at 25 °C.; the pH of a 10% aqueous solution of piperazine is 10.8–11.8. Piperazine readily absorbs water and carbon dioxide from the air.

How to calculate the pKa value of phenazine?

pKa Data Compiled by R. Williams page-1 pKa Values INDEX Inorganic 2 Phenazine 24 Phosphates 3 Pyridine 25 Carboxylic acids 4, 8 Pyrazine 26 Aliphatic 4, 8 Aromatic 7, 8 Quinoline 27 HCO3 10.33* HSe– 11.00* 77 H2CrO4 -0.98 30 H 2S 7.00* 77 HCrO4 6.50* 2, 30 HS– 12.92* 77 HOCN 3.92 34

What is the standard state of N-methylpiperazine?

Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N-Methylpiperazine is a heterocyclic organic compound . N -Methylpiperazine is a common building block used in organic synthesis.