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What is the cause of keratoderma?

What is the cause of keratoderma?

What causes palmoplantar keratoderma? Keratoderma may be inherited (hereditary) or, more commonly, acquired. The hereditary keratodermas are caused by a gene abnormality that results in abnormal skin protein (keratin). They may be inherited either by an autosomal dominant or autosomal recessive pattern.

How is keratoderma treated?

Treatment

  1. Saltwater soaks.
  2. Emollients.
  3. Paring (cutting away layers of skin)
  4. Topical keratolytics (useful for people with limited keratoderma)
  5. Topical retinoids (this is often limited by skin irritation)
  6. Systemic retinoids (acitretin)
  7. Topical vitamin D ointment (calcipotriol)

What is a keratoderma mean?

Keratoderma is a heterogeneous group of disorders of keratinization defined by the presence of focal or generalized thickening of the skin of the palms and/or soles.

Is keratoderma itchy?

The rashes over the hands and feet considerably increased to alter the texture of the skin and to occupy their current position. Itching and/or pain were its preeminent features. Profuse sweating of the affected part was also an attribute.

What kind of skin does palmoplantar keratoderma have?

The term palmoplantar keratoderma describes a diverse group of skin conditions affecting the hands and feet—specifically the palms and the soles (also known as the plantar region of the foot, hence the name “palmo- plantar keratoderma”). Keratoderma means “thickened skin.”

Which is the most common symptom of keratoderma?

These are the most common symptoms of keratoderma blennorrhagicum: Lesions in the form of pustules or vesicles appear on the skin. Lesions have a waxy texture. The color of the lesions can range from yellow to brown.

What does keratoderma look like on the foot?

The affected skin acquires a reddish, flaky appearance and eventually hardens into thick, yellowish pads of callus. Depending on which type of keratoderma the person suffers from, it can affect the entire sole of the foot or it may appear in streaks or patches, possibly mimicking the appearance of corns.

Where does Keratoderma blennorrhagicum appear on the body?

The condition manifests itself by lesions that appear on the skin, initially on the palm of the hands and soles of the feet. The lesions have the tendency to spread, affecting other parts of the body, such as the scrotum, scalp or trunk.