What is CMV DNA PCR test?

Quantitative CMV DNA PCR testing provides a “viral load” value useful for. monitoring antiviral therapy and possible identifying patients at risk for CMV disease. Clinical Significance: Human Cytomegalovirus (CMV) is a member of the Herpes Virus.

How do you interpret CMV PCR results?

A result of “<35 IU/mL (<1.54 log IU/mL)” indicates that CMV DNA is detected in the plasma, but the assay cannot accurately quantify the CMV DNA present below this level. A quantitative value (reported in IU/mL and log IU/mL) indicates the level of CMV DNA (ie, viral load) present in the plasma.

What is CMV quant DNA PCR plasma?

CMV is also the most common cause of congenital viral infection in humans. Quantitative PCR methods may be useful in monitoring CMV replication in immunosuppressed patients or in determining the viral load of CMV in amniotic fluid. This is a quantitative molecular test, with a linear range of 200-2,000,000 IU/mL.

What is cytomegalovirus DNA quantitative real time PCR?

A real-time PCR assay was developed to quantify human cytomegalovirus (CMV) DNA. This assay was used to demonstrate a higher CMV DNA load in plasma of bone marrow transplant patients than in that of blood donors. The CMV load was higher in CMV antigen-positive patients than in antigen-negative patients.

What does CMV PCR positive mean?

A positive CMV DNA test may mean CMV is present and you have, or the newborn tested, has an active infection. High levels of viral DNA may indicate a more severe infection with serious symptoms.

Is CMV curable?

CMV spreads from person to person through body fluids, such as blood, saliva, urine, semen and breast milk. There is no cure, but there are medications that can help treat the symptoms.

Is CMV a STD?

CMV can be sexually transmitted. It can also be transmitted via breast milk, transplanted organs and, rarely, blood transfusions. Although the virus is not highly contagious, it has been shown to spread in households and among young children in day care centers.

Is CMV a DNA virus?

Human cytomegalovirus (HCMV) is classified as a DNA herpesvirus. A recent study showed that the HCMV virion contains not only DNA, but also four species of mRNA, indicating that this virus is more complex than previously believed.

What happens if you are CMV positive?

The majority of children born who experience a CMV infection before birth are healthy and normal. However, 10 to 15% may have complications such as hearing loss, neurological abnormalities, or decreased motor skills. Infants who are infected with CMV after they are born rarely experience any long-term complications.

Is CMV virus an STD?

What happens if CMV is left untreated?

If untreated, it can spread throughout the body, infecting organ after organ. It may cause respiratory problems, damage to the central nervous system, bleeding ulcers in the digestive system, and CMV retinitis, which can lead to blindness.

Can I use CMV positive sperm?

Some doctors say that sperm donors who are tested IgG positive (which means they have previously had the infection) may only be used for women who themselves are IgG positive. This means that if you know that you have previously been infected with CMV, you can use a sperm donor with a positive CMV status.