What is anti Lkm blood test?

This test detects and measures the amount (titer) of anti-LKM-1 (or antibody against CYP2D6) in the blood. Autoimmune hepatitis is an acute or chronic inflammation of the liver that can lead to liver cirrhosis and, in some cases, to liver failure.

What is LKM 1 antibody IgG?

Liver Kidney Microsomal (LKM-1) Antibody (IgG) – The presence of LKM-1 antibodies can be used in conjunction with clinical findings and other laboratory tests to aid in the diagnosis of autoimmune liver diseases such as autoimmune hepatitis (AIH-2).

What is liver kidney microsomal antibody test?

This test looks for a certain type of antibody in your child’s blood. The antibody is called liver kidney microsomal antibody. Having this antibody may mean that your child has liver damage caused by a form of hepatitis. Hepatitis is a condition in which the liver is inflamed.

What does a positive Asma mean?

The presence of ASMA in the blood indicates that a person may have autoimmune hepatitis or another disease that damages the liver.

What is the difference between Type 1 and Type 2 autoimmune hepatitis?

Type 1 AIH, also referred to as the classic type, is typically diagnosed in adulthood, whereas type 2 is diagnosed during childhood. Both types are treated similarly; however, type 2 AIH can be more severe and more difficult to control.

What does equivocal mean in blood test?

Equivocal antibody test results mean that the results could not be interpreted as positive or negative. Reasons for this may include: There is an immune response but it’s not strong enough to give a positive result.

What is the difference between type 1 and Type 2 autoimmune hepatitis?

What is anti SLA?

Anti-Soluble-Liver-Antigen autoantibodies (SLA) are specifically associated with type 1 and type 2 autoimmune hepatitis and more closely related to patients who relapse after steroid therapy.

What is the survival rate for autoimmune hepatitis?

Without treatment, approximately 40% to 50% of the individuals with severe disease will die within 6 months to 5 years. Treatment with steroids has dramatically changed the course of the disease. Most patients respond to therapy and the 10-year survival rate is approximately 83.8% to 94%.

What does it mean if your anti LKM 1 test is negative?

If your results show a negative anti-LKM 1, but SMA and ANA tests are positive, it may mean that you have type 1 autoimmune hepatitis. However, if all are negative, it may be that your liver disease is not caused by autoimmune diseases. The possibility is, however, not ruled out as sometimes as not all people produce anti-LKM 1 or SNA antibodies.

How does anti LKM-1 affect your prognosis?

Levels of anti-LKM-1 are not closely related to the severity of a person’s symptoms or to that person’s prognosis. Levels may vary over time. Those with type 2 autoimmune hepatitis may also have other autoimmune disorders, such as diabetes or thyroiditis.

What kind of hepatitis is associated with anti LKM-1 antibodies?

The development of anti-LKM-1 antibodies is strongly associated with type 2 autoimmune hepatitis. This test detects and measures the amount (titer) of anti-LKM-1 (or antibody against CYP2D6) in the blood. Autoimmune hepatitis is an acute or chronic inflammation of the liver that can lead to liver cirrhosis and, in some cases, to liver failure.

When to use LKM or liver microsomal antibody test?

LKM Antibody Test What is LKM Antibody Test? LKM or liver-kidney microsomal antibody is any of the various antibodies that are detected in the serum who suffer from different kinds of acute or chronic liver diseases. It is used if you have liver diseases that have unknown causes or if you are suffering from autoimmune hepatitis.