What is a vesicant IV?

The most severe type of IV Infiltration usually occurs when highly caustic medications known as vesicants infiltrate the tissues surrounding the IV site causing burns and tissue necrosis, a process called IV Extravasation.

How are vesicant drugs administered?

Peripheral vesicants are administered by gravity infusions or i.v. bolus and should not be infused using an infusion pump since the pump may continue to deliver a vesicant into the tissue until the pump alarm is triggered (AIII).

What is the meaning of vesicant drugs?

tissue blistering
Vesicant: A substance that causes tissue blistering. Also known as vesicatory.

When infusing vesicant medication what is best practice?

Inject or infuse the vesicant medication through the Y-site needleless connector of a free-flowing I.V. solution, such as 0.9% sodium chloride solution. This additional fluid helps dilute the drug and reduces the risk of vein damage.

What are examples of vesicant drugs?

Vesicants: Drugs that can result in tissue necrosis or formation of blisters when accidentally infused into tissue surrounding a vein[14]. They include Actinomycin D, Dactinomycin, Daunorubicin, Doxorubicin, Epirubicin, Idarubicin, Mitomycin C, Vinblastine, Vindesine, Vincristine, and Vinorelbine.

Which drug is most risky for extravasation?

Chemotherapeutic agents have obvious deleterious effects when extravasation occurs and can lead to more severe injury. These drugs can be classified as irritants or vesicants, depending on the potential for localised toxicity and tissue damage….

• thiopentone [pH 10.5],
• methohexitone [pH 11.5–12.2],
• phenytoin [pH 12].

What are non vesicant drugs?

Examples of non-vesicant solutions and medications include: Lactated ringers. Many antibiotics. Solumedrol (steroid) Ondansetron (Zofran) – anti-nausea drug. Furosemide (Lasix) – IV diuretic.

What does vesicant extravasation mean?

Extravasation occurs when a vesicant drug leaks out of the vein and into the surrounding tissue. When this happens, a person will likely experience serious tissue damage, including ulceration and tissue death, if they do not receive treatment in time.

Which chemical is a vesicant?

The following chemicals were chosen to represent the entire class of vesicants. Vesicants include distilled mustard (HD), mustard gas (H), mustard/lewisite, mustard/T, nitrogen mustard, sesqui mustard, and sulfur mustard.

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