What does high creatinine and low GFR mean?

GFR is the best measure of kidney function but both creatinine and GFR can be useful indicators of your kidney health. If GFR goes down, it’s a bad sign. If creatinine goes up, it’s a bad sign. In general, a “good” GFR number is above 60 and a “good” creatinine number is below 1.2.

What level of BUN and creatinine indicates kidney failure?

A GFR below 60 is a sign that the kidneys are not working properly. Once the GFR decreases below 15, one is at high risk for needing treatment for kidney failure, such as dialysis or a kidney transplant. Urea nitrogen comes from the breakdown of protein in the foods you eat. A normal BUN level is between 7 and 20.

Does BUN affect GFR?

BUN is not a reliable index of GFR. The kidney tubules reabsorb urea in quantities that vary depending on the state of hydration, thus rendering BUN an inaccurate marker for GFR. BUN concentration is also strongly affected by changes in catabolism and protein intake.

What causes GFR to drop?

A decrease or decline in the GFR implies progression of underlying kidney disease or the occurrence of a superimposed insult to the kidneys. This is most commonly due to problems such as dehydration and volume loss. An improvement in the GFR may indicate that the kidneys are recovering some of their function.

Should I worry if my GFR is 50?

If the function is somewhat low but stable, you may need to see your doctor only once per year. If the GFR is declining or it is already under 50, it’s best to see a kidney doctor, if for no other reason than to become educated.

Should I worry if my eGFR is 54?

An estimated glomerular filtration rate (eGFR) of less than 60 milliliters per minute per 1.73 meters squared for greater than 3 months is suggestive of chronic kidney disease (CKD) Stage 3. The number 50 and 54 are not significantly different from each other. This is within expected laboratory variability.

What is the creatinine level for stage 2 kidney disease?

An abnormally high creatinine level means your kidneys aren’t functioning at an optimal level. EGFR readings that are 90 or higher occur in stage 1 CKD, where there’s extremely mild kidney damage. Kidney failure is seen in readings of 15 or below. With stage 2, your eGFR reading will fall between 60 and 89.

What is the significance of low bun?

If the BUN levels are not normal, they indicate a flaw in the body’s flushing system. High level of BUN is a sign of kidney dysfunction, while low BUN levels can indicate liver problems.

What do low blood urea nitrogen (BUN) levels mean?

Blood urea nitrogen : Or bun, is an indicator of kidney function, fluid balance, muscle turnover (breakdown and rebuilding). Normal BUN is between 7 and 20. A low BUN could be seen in a person with lower muscle mass or low muscle use (ex a paraplegic person) where there is less muscle turnover…

What does a low creatinine level mean?

Low blood creatinine levels. Low blood creatinine levels can mean lower muscle mass caused by a disease, such as muscular dystrophy, or by aging. Low levels can also mean some types of severe liver disease or a diet very low in protein.

What cause high glomerular filtration rate (GFR)?

GFR can increase due to Hypoproteinemia because of the reduction in plasma oncotic pressure. GFR can also increase due to constriction of the efferent arteriole due to High blood pressure.