Is thalassemia same as sickle cell disease?
Is thalassemia same as sickle cell disease?
Sickle beta thalassemia is an inherited condition that affects hemoglobin, the protein in red blood cells that carries oxygen to different parts of the body. It is a type of sickle cell disease.
What is sickle cell thalassemia?
Sickle cell disease and thalassemia are genetic disorders caused by errors in the genes for hemoglobin, a substance composed of a protein (“globin”) plus an iron molecule (“heme”) that is responsible for carrying oxygen within the red blood cell.
Can you have thalassemia and sickle cell?
One parent carries sickle trait, which causes no health problems for him or her. The other carries the trait for beta+ thalassemia, which sometimes causes a mild anemia (low blood count), but usually no symptoms. When these traits come together in the same person, the result is sickle-beta+-thalassemia.
How do you get sickle cell thalassemia?
People only have sickle cell disease or thalassaemia if they inherit 2 unusual haemoglobin genes: 1 from their mother and 1 from their father. People who inherit just 1 unusual gene are known as carriers or as having a trait.
What should sickle cell patients avoid?
avoid very strenuous exercise – people with sickle cell disease should be active, but intense activities that cause you to become seriously out of breath are best avoided. avoid alcohol and smoking – alcohol can cause you to become dehydrated and smoking can trigger a serious lung condition called acute chest syndrome.
Is Sickle Cell curable?
Stem cell or bone marrow transplants are the only cure for sickle cell disease, but they’re not done very often because of the significant risks involved. Stem cells are special cells produced by bone marrow, a spongy tissue found in the centre of some bones.
What is sickle cell pain like?
The pain may feel sharp, stabbing, intense, or throbbing. Some people with sickle cell disease say it’s worse than childbirth or the pain after surgery. You may have pain anywhere in your body and in more than one place.
Can thalassemia turn into leukemia?
Occurrence of leukemia in thalassemia major is a rare presentation. Here we report two cases of thalassemic patients, developing acute lymphoblastic leukemia. The genetic analysis revealed that, female and male patients were homozygous for IVSI-6 and IVSI-5, respectively.
What blood type carries sickle cell?
It is an inherited condition in which both hemoglobin A and S are produced in the red blood cells, always more A than S. Individuals with sickle cell trait are generally healthy.
How do I know my sickle cell status?
The best way to check for sickle cell trait or sickle cell disease is to look at the blood using a method called high-performance liquid chromatography (HPLC). This test identifies which type of hemoglobin is present. To confirm the results of HPLC, a genetic test may be done.
Does cold weather affect sickle cell?
Exposure to cold air, wind, and water can trigger a sickle cell crisis. Dress children in warm layers of clothing for cold-weather activities.
Is banana good for sickle cell?
For example, pomegranates increase blood flow, and fruits and vegetables such as bananas and kale boost energy levels. These benefits are especially advantageous for people with sickle cell anemia. Increased blood flow reduces the chance of a sickle cell crisis, while more energy helps us to combat fatigue.
What is the genetic cause of beta thalassemia?
Beta Thalassemia Major is caused by genetic mutation of the beta-globin gene on chromosome 11 and both copies of the gene are affected.
Is thalassemia the same as sickle cell anemia?
Thalassemia is not same as sickle cell anemia disease. They both are different, in sickle cell anemia, the shape of the RBCs or the red blood corpuscles are sickle shaped, which are unable to carry sufficient amount of oxygen to the other body cells, whereas in case of Thalassemia there is lack…
Is sickle cell a curable disease?
Sickle cell anemia is a disease that for the most part cannot be cured. Most people cope with Sickle cell because it is so hard to find a person to help with their cure. A way to cure Sickle cell anemia is to receive a bone marrow transplant to replace the red blood cells.
How is thalassemia different from sickle cell anaemia?
The key difference between sickle cell anemia and thalassemia is that in thalassemia, both α and β globin chains can be affected but in sickle cell anemia only the β globin chains are affected. 1. Overview and Key Difference