How does Smoflipid differ from intralipid?

Given the various oils in Smoflipid, the primary concern with dispensing this product instead of Intralipid is with patients who have an allergy to fish (which poses no problem with Intralipid). Also, unlike Intralipid, Smoflipid does not have a pediatric indication if dispensed in error to this population.

When do you use SMOF lipids?

Smoflipid is indicated in adults as a source of calories and essential fatty acids for parenteral nutrition when oral or enteral nutrition is not possible, insufficient, or contraindicated.

What does SMOF stand for lipids?

SMOF (20%) stands for Soya oil (6%), Medium chain triglycerides (6%), Olive oil (5%), Fish. oil (3%) Final volume contains 17% fat providing 1.7kcal/mL.1mL of fat emulsion is equivalent to 0.17g. of fat. Dose and Indications.

What does SMOF stand for TPN?

Induced Liver Injury
SMOF Lipid for Children With Parenteral Nutrition Induced Liver Injury (SMOF) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators.

What is the lipid content of smoflipid injection?

Smoflipid is a sterile, nonpyrogenic, white, homogenous lipid emulsion for intravenous infusion. The lipid content of Smoflipid is 0.20 g/mL, and comprises a mixture of soybean oil, medium-chain triglycerides (MCTs), olive oil, and fish oil.

How is smoflipid used in central venous infusion?

Smoflipid is for central or peripheral intravenous infusion. When administered with dextroseand amino acids, the choice of a central or peripheral venous route should depend on the osmolarityof the final infusate. Solutions with osmolarity of ≥ 900 mOsm/L must be infused through a central vein. Use a 1.2 micron in-line filter.

How long does it take for a smoflipid infusion?

The recommended duration of infusion for Smoflipid is between 12 and 24 hours, depending on the clinical situation. The administration flow rate is determined by dividing the volume of lipid by the duration of the infusion.

Why does smoflipid cause fat overload syndrome?

Fat overload syndrome occurred as a result of accidental, very rapid infusion of a 20% soy oil, medium-chain triglyceride, olive and fish oil-based lipid emulsion (SMOFlipid) that showed the same complications seen with an earlier lipid emulsion (Intralipid).