Useful tips

How do you treat ventriculitis?

How do you treat ventriculitis?

Antibiotics are the mainstay of treatment. This activity will review the causes of ventriculitis and the different microbes responsible. It will evaluate the different investigations required for diagnosis and review the treatment options available.

How is neonatal meningitis treated?

Antibiotic choices for neonatal meningitis include ampicillin and gentamicin or cefotaxime. For infants younger than 8 days old, the dose for Ampicillin is 150 mg/kg per day divided every 8 hours, plus gentamicin 4 mg/kg daily or cefotaxime 100 to 150 mg/kg per day divided every 8 to 12 hours.

What is the difference between ventriculitis and meningitis?

It is important to note that, though they present with similar symptoms and often occur in tandem, meningitis and ventriculitis are two different diseases, so physicians must be able to distinguish between the two. Meningitis is the inflammation of the protective lining of the central nervous system, called meninges.

What antibiotics can be given to neonates?

Recommended Dosages of Selected Oral Antibiotics for Neonates*

Interval of Administration
Antibiotic Dose Body Weight > 2000 g
Amoxicillin (may be combined with clavulanate) 15 mg/kg Every 12 hours
Azithromycin 10 mg/kg Every 24 hours
Clindamycin 5–9 mg/kg 7 mg/kg every 8 hours

Is it necessary to diagnose and treat ventriculitis?

Ventriculitis is a potentially life-threatening infection, and an early diagnosis is essential for the appropriate treatment of ventriculitis. With the available literature, it is difficult to document the frequency with which ventriculitis exists, and also failure to recognize this entity might account for the scant literature.

Is there an in vitro susceptibility test for ventriculitis?

However, given the increasing frequency of antimicrobial resistance among gram-negative bacilli, especially in the hospital setting, in vitro susceptibility testing of isolates is critical to guide antimicrobial therapy.

What should the CSF level be for ventriculitis?

An increase in the CSF protein level (>50 mg/dL), or a finding of neutrophilic pleocytosis (>10 cells/μL).

What kind of bacterial infection can cause ventriculitis?

Ventriculitis frequently accompanies neonatal bacterial meningitis, particularly when caused by gram-negative enteric bacilli. Organisms that cause meningitis together with severe vasculitis, particularly C. diversus and Cronobacter sakazakii (formerly Enterobacter sakazakii ), are likely to cause cysts and abscesses.