Can Pseudolymphoma turn into lymphoma?

Although rare, reports of cutaneous B-cell pseudolymphoma evolving into B-cell lymphoma have been described. In one study of 4 cases, transformation of 1 case of pseudolymphoma into a large B-cell lymphoma was identified, similar to our patient [7].

What is cutaneous Pseudolymphoma?

Cutaneous pseudolymphoma refers to a heterogeneous group of benign reactive T- or B-cell lymphoproliferative processes of diverse causes that simulate cutaneous lymphomas clinically and/or histologically.

How is Pseudolymphoma treated?

In idiopathic cases of cutaneous pseudolymphoma, treatment is not mandatory. Cures may be effected via surgical removal, cryosurgery, or local irradiation. Some reports have noted a response to topical or injected corticosteroids and topical immunomodulators such as tacrolimus.

What does Pseudolymphoma mean?

Pseudolymphoma is not a specific disease but rather an inflammatory response to known or unknown stimuli that results in a lymphomatous-appearing but benign accumulation of inflammatory cells.

What does cutaneous pseudolymphomas mean in medical terms?

The term cutaneous pseudolymphoma refers to benign reactive lymphoid proliferations in the skin that simulate cutaneous lymphomas. It is a purely descriptive term that encompasses various reactive conditions with a varied etiology, pathogenesis, clinical presentation, histology, and behavior. We pre …

When to rebiopsy a case of pseudolymphoma?

However, some cases of pseudolymphoma of the skin can persist for years (certain cases of CLH) – rebiopsy in that situation should occur when the clinical presentation/behavior appears to change from the initial presentation. Clinicopathologic correlation is crucial for diagnosis of cutaneous pseudolymphoma vs. cutaneous lymphoma.

Are there adjunctive studies for pseudolymphoma dermatology?

Adjunctive studies to rule out underlying infection, inflammatory conditions can be done on a case-by-case basis (HIV, rapid plasma reagin (RPR), Lyme titer, connective tissue serologies).

What kind of steroid do you use for pseudolymphoma?

For recurrent lesions, treatment is intralesional steroid injections (triamcinolone 5mg/ml on face, 10mg/ml elsewhere, to start).

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