Users' questions

What is duodenal gastric Heterotopia?

What is duodenal gastric Heterotopia?

Duodenal gastric heterotopia (DGH) is a common incidental finding at endoscopy, generally assumed to be congenital in origin. A recent study has suggested a possible association with gastric fundal gland polyps (FGPs).

What is heterotopic mucosa?

Heterotopic gastric mucosa (HGM) is gastric mucosal tissue outside the stomach. It can be discovered anywhere throughout the gastrointestinal tract and is mostly asymptomatic.

What does duodenal mucosa mean?

Transitional-type duodenal mucosa, one of the three types of normal mucosa, is also referred to as gastric epithelium or gastric surface epithelial metaplasia. Evidence is presented to support the view that this is a normal finding and is not an indication of duodenitis.

What is the duodenal bulb?

The duodenal bulb refers to a proximal-most portion of the duodenum closest to the stomach and for most of the D1 segment of the duodenum. It usually has a length of about 5 cm. It commences at the gastric pylorus and ends at the neck of the gallbladder.

How is heterotopia of the duodenal bulb differentiated?

It must be differentiated from gastric metaplasia of the duodenal bulb because the two entities have different clinical implications. During one year, we found three cases of gastric heterotopia of the duodenal bulb. In one of the cases, active acid-secreting gastric mucosa was documented by performing the pentagastrin Congo red dye test.

What does nodular bulb duodenal mucosa stand for?

Nodular duodenal mucosa corresponding to a bulbar island of gastric heterotophia (a-classical videoendoscopy, b-FICE chromoendoscopy) Figure 4. Heterotopic gastric mucosa at the duodenum level similar to folds (a) and gastric areas (b) of the gastric body

Is there heterotopic mucosa in the duodenum?

This consisted of multiple small mucosal nodules, predominantly in the anterior wall. All cases were biopsied, and showed identical histological appearances of heterotopic gastric mucosa of body type. The incidence of this condition is probably much higher than reported previously, and may be present in up to 2% of the population.

Where does Heterotopic gastric mucosa ( HGM ) occur?

Heterotopic gastric mucosa (HGM) can be identified anywhere in the digestive tract [1]: tongue [2], esophagus [3], duodenum [4,5], jejunum [6], ileum [7], Meckel diverticulum [8], colon, rectum [9,10], anus [11] and gallbladder [12]. In duodenum was first reported at necropsy (Taylor in 1927).

What is normal duodenal mucosa?

Generally, normal duodenal mucosa shows long villi with a villous-to-crypt ratio of 3:1 as well as a normal number of intraepithelial lymphocytes (<30). Based on histologic changes in lymphocytic infiltration, crypt hyperplasia, and villous atrophy shown in Fig.

What is inflammation of the duodenum?

Duodenitis is an intestinal condition caused by inflammation in your duodenum lining. It can sometimes happen along with gastritis, which is inflammation in your stomach lining. When they happen together, they are called gastroduodenitis.

What is intestinal metaplasia of gastric mucosa?

Gastric intestinal metaplasia is a precancerous change of the mucosa of the stomach with intestinal epithelium, and is associated with an increased risk of dysplasia and cancer.

What happens when your duodenum is inflamed?

Duodenitis is inflammation occurring in the duodenum, the beginning of the small intestine. Inflammation in the lining of the duodenum may result in abdominal pain, bleeding, and other gastrointestinal symptoms.

What should I eat if I have Duodenitis?

Eat a variety of healthy foods. Examples include fruits (not citrus), vegetables, low-fat dairy products, beans, whole-grain breads, and lean meats and fish. Try to eat small meals, and drink water with your meals.

What is the purpose of duodenal bulb?

The first segment of the duodenum—the superior part of the duodenum (called the duodenal bulb) is connected to the liver via the hepatoduodenal ligament. This connection allows for transportation of nutrients from the small intestine to the liver; it also allows the duodenum to receive bile from the liver.

What can go wrong with the duodenum?

Inflammation in the lining of the duodenum may result in abdominal pain, bleeding, and other gastrointestinal symptoms. The most common cause of duodenitis is a stomach infection associated with a type of bacteria called Helicobacter pylori (H pylori).

What does duodenum pain feel like?

The main symptom of a stomach or duodenal ulcer is upper abdominal pain, which can be dull, sharp, or burning (a hunger-like feeling). (Bloating and burping are not symptoms of peptic ulcer, and vomiting, poor appetite, and nausea are uncommon symptoms of peptic ulcer.)

How is inflamed duodenum treated?

Medications such as proton pump inhibitors and histamine H2-receptor antagonists, which decrease the amount of acid in the stomach, can also be an effective treatment for duodenitis. Proton pump inhibitors that may be effective in the treatment of duodenitis include: Esomeprazole (Nexium) Lansoprazole (Prevacid)

How is Heterotopic gastric mucosa detected in the duodenum?

Heterotopic gastric mucosa in the duodenal bulb was detected by endoscopic examination in 25 adult patients and was confirmed by biopsy in 17 of these patients. The endoscopic findings were correlated with the radiographic features of the lesion on upper gastrointestinal barium studies.

Are there any cases of heterotopia in the duodenal bulb?

During one year, we found three cases of gastric heterotopia of the duodenal bulb. In one of the cases, active acid-secreting gastric mucosa was documented by performing the pentagastrin Congo red dye test. The differences between gastric heterotopia of the duodenal bulb and gastric metaplasia of the duodenal bulb have been discussed.

Is there an ectopic fundic mucosa in the duodenum?

The unexpected detection of ectopic gastric fundic-type mucosa within the duodenum has been described for over 80 years. This duodenal gastric heterotopia (DGH) was initially assumed to be congenital in origin, one of a variety of congenital heterotopias which occur along the length of the gastrointestinal tract.

How is duodenal heterotopia related to fundic gland polyps?

Duodenal gastric heterotopia: further evidence of an association with fundic gland polyps. Summary. Duodenal gastric heterotopia (DGH) is a common incidental finding at endoscopy, generally assumed to be congenital in origin. A recent study has suggested a possible association with gastric fundal gland polyps (FGPs).