What is disodium cromoglycate?

Disodium cromoglycate is an organic sodium salt that is the disodium salt of cromoglycic acid. It has a role as an anti-asthmatic drug and a drug allergen. It contains a cromoglycate(2-).

What is cromoglycate mention its mechanism?

Cromoglicate inhibits degranulation of mast cells, subsequently preventing the release of histamine and slow-reacting substance of anaphylaxis (SRS-A), mediators of type I allergic reactions. Cromoglicate also may reduce the release of inflammatory leukotrienes. Cromoglicate may act by inhibiting calcium influx.

Is disodium cromoglycate a bronchodilator?

Cromolyn sodium does not have a bronchodilator effect; therefore it is exclusively a prophylactic agent and has no bearing on anesthetic practice. It attenuates bronchoconstriction caused by allergen, exercise, and bronchial challenge (Stempel, 2003).

Is cromolyn a brand name?

BRAND NAME(S): Intal. USES: This medication is used to prevent symptoms (wheezing and shortness of breath) caused by asthma.

What is the brand name for cromolyn sodium?

BRAND NAME(S): Gastrocrom. USES: This medication is used in people with a food allergy to prevent serious reactions to foods. It is also used to treat and prevent inflammatory bowel diseases (e.g., ulcerative colitis). Cromolyn belongs to a class of medications called mast cell stabilizers.

Can you buy cromolyn sodium over the counter?

The mast-cell stabilizer cromolyn sodium is available for over-the-counter (OTC) use in the prevention and treatment of allergic rhinitis.

How quickly does sodium cromoglycate work?

How long does sodium cromoglycate take to work? Your child may start feeling better several days after starting this medicine. It may take up to 4 weeks after your child starts taking sodium cromoglycate before this medicine has full effect.

What is another name for cromolyn?

BRAND NAME(S): Gastrocrom. USES: This medication is used in people with a food allergy to prevent serious reactions to foods.

What drugs are mast cell stabilizers?

List of Mast cell stabilizers:

Is sodium cromoglycate a mast cell stabilizers?

Sodium cromoglicate is a mast cell stabiliser, which means it reduces the amount of chemicals released by the mast cells. This helps relieve symptoms such as diarrhoea, bone pain, fatigue and headache. Some people taking sodium cromoglicate have reported feeling sick and getting joint pain.

Which is the best description of cromoglycate disodium?

Cromoglycate Disodium. Cromoglycic acid (cromolyn sodium) is an anti-inflammatory agent that prevents mast cell activation and degranulation by inhibiting chloride transport and protein kinase C. Cromoglycic acid can also inhibit neutrophil chemotaxis and free radical-induced neutrophil NADPH oxidase.168.

How many mg of cromoglicate disodium salt are there?

Cromoglicate disodium salt (cromoglicate sodium) is available as a powder for inhalation. Each capsule contains 20 mg. The usual dose is 1 capsule inhaled four times daily. It is also dispensed in a multidose-pressurized aerosol delivering 1 or 5 mg per actuation.

What kind of Medicine is sodium cromoglicate for?

About sodium cromoglicate Type of medicine An anti-asthma medicine Used for To prevent asthma symptoms (in adults an Also called Cromolyn sodium (in US); Intal® Available as Inhaler

How does cromoglycate and Nedocromil sodium affect mast cells?

Cromoglycate and nedocromil Sodium cromoglycate and nedocromil sodium are both drugs that have been demonstrated to influence mast cell degranulation in in vitro studies. However, no inhibitory effect on histamine release has been demonstrated in mast cells recovered from nasal tissue.