What is an anterior synechiae?

Anterior synechiae are at the angle of the eye where the peripheral iris impedes aqueous drainage and can lead to angle closure glaucoma. Posterior synechiae are at the pupil margin where the iris is adherent to the anterior lens capsule, which prevents dilation and makes cataract surgery more challenging.

What is the definition of synechiae?

The term synechiae comes from the Greek synekhes, which means “hold together.” Synechiae are adhesions that may occur anteriorly in which the iris becomes adherent to the trabecular meshwork in the iridocorneal angle (peripheral anterior synechiae, PAS) or occur posteriorly in which the iris adheres to the anterior …

Why is posterior synechiae?

Posterior synechiae occur when fibrinous adhesions form between the lens and iris, with fibrovascular organization occurring later (see Figure 11-24). Formation of synechiae is more likely when aqueous protein content is high.

What is peripheral synechiae?

Peripheral anterior synechiae (PAS) refers to a condition in which the iris adheres to the angle. PAS can develop in various ocular conditions, including: ocular inflammation, a post-traumatic condition, after cataract surgery, or with an iris bombe in a pupillary block glaucoma.

How is peripheral anterior synechiae treated?

Medical Care

1. Topical α-agonists, β-blockers, carbonic anhydrase inhibitors, and prostaglandin agonists may be useful in lowering intraocular pressure in eyes with PAS.
2. Miotics are useful in the treatment of pupil block due to primary angle-closure but may exacerbate angle closure due to posterior pushing mechanisms.

How do you break iris synechiae?

By utilizing a pledget, a small wad of cotton, we can administer a large, sustained dose of dilating agents to break the synechia. After the pledget is removed, re-evaluate the pupil and synechia. Upon discharge, patients are prescribed the appropriate anti-inflammatory agents as well as a cycloplegic agent.

Is posterior synechiae curable?

This is a treatable status. To subdue inflammation, topical corticosteroids can be used.

What causes peripheral anterior synechiae?

Peripheral anterior synechiae result from prolonged appositional contact between the iris and trabecular meshwork (as in primary angle-closure glaucoma) or from anterior chamber inflammation or neovascularization (secondary angle-closure glaucoma).

Is anterior synechiae painful?

Peripheral anterior synechiae (PAS) can present in the following ways: Acute angle closure with the classic constellation of symptoms, including ocular pain, headaches, blurred vision, and haloes.

How do you break Synechiae?

Can the iris change shape?

The edge of the pupil may turn outward (ectropion uveae). The onset of this disorder is gradual, and the changes in the shape and placement of the pupil are usually noticed before any change in vision occurs. Degeneration and holes in the iris may develop over a period of several years.

Can you break peripheral anterior synechiae?

It is possible, although unlikely, to break a pupil block or early PAS by performing anterior chamber compression using a gonioprism such as a Zeiss goniolens. Indicated when pupil block is the cause of or contributes to the formation of PAS.

What does posterior synechia mean?

Princeton’s WordNet (0.00 / 0 votes)Rate this definition: posterior synechia (noun) adhesion between the iris and the lens.

What does Anterior synechia mean?

Princeton’s WordNet (0.00 / 0 votes)Rate this definition: anterior synechia (noun) adhesion between the iris and the cornea.

What is peripheral anterior synechiae inyour eye?

Peripheral anterior synechiae (PAS) are adhesions of the peripheral iris to the structures in the angle of the anterior chamber . They may be associated with a variety of conditions such as angle closure glaucoma, neovascular glaucoma, uveitis, and iridocorneal endothelial (ICE) syndrome.