What happens if valproic acid level is too high?

The valproic acid level in the blood must be maintained within a narrow therapeutic range. If the level is too low, someone may experience a recurrence of symptoms, but, if the level is too high, someone may experience an increase in the number and severity of symptoms and side effects.

How high does Depakote go?

Depakote tablets are administered orally. The recommended starting dose is 250 mg twice daily. Some patients may benefit from doses up to 1,000 mg/day. In the clinical trials, there was no evidence that higher doses led to greater efficacy.

How do you feel on Depakote?

Common side effects

1. Nausea or vomiting.
2. Headache.
3. Drowsiness or dizziness.
4. Tremor.
5. Muscle weakness.
6. Insomnia.
7. Hair loss.
8. Weight gain.

Is 2000 mg of Depakote a lot?

The mean daily dose usually ranges between 1000 – 2000 mg valproate. Patients receiving daily doses higher than 45 mg/kg/day body weight should be carefully monitored. Continuation of treatment of manic episodes in bipolar disorder should be adapted individually using the lowest effective dose.

How does Depakote make you feel?

A: Common side effects experienced with Depakote include drowsiness, nausea, abdominal pain, diarrhea, vomiting, low platelet count, tremors, tiredness, and hair loss. The side effects may be mild to moderate, but they may also be signs of a more serious condition.

What happens if you OD on Depakote?

An overdose of Depakote could be fatal, so seek immediate help or call the Poison Help Line at 1-800-222-1222 if you overdose. Overdose symptoms can include irregular heartbeat, sleepiness, and loss of consciousness resulting in a coma.

Do Depakote levels need to be monitored?

Patients should be monitored closely for appearance of these symptoms. Serum liver tests should be performed prior to therapy and at frequent intervals thereafter, especially during the first six months [see Warnings and Precautions (5.1)].

Is 1000 mg Depakote too much?

The recommended starting dose of Depakote for the prevention of migraine is 250 mg twice daily. The dose may be increased until migraine control is achieved. The maximum recommended dose is 1000 mg/day as needed.

What does Depakote make you feel like?

Does Depakote make you feel weird?

What happens if your Depakote level is too high?

If your Depakote level dips below its therapeutic level, the drug may become less effective. If it rises too high, the drug can become toxic, causing possible damage to the pancreas or liver. So remember: Always take the prescribed dose.

What are the signs of too much Depakote?

Intravenous fluids may be given to someone experiencing a Depakote® overdose. Potential signs of a Depakote overdose include extreme drowsiness and low blood pressure. Depakote might be linked to insomnia.

What are the signs of a Depakote& overdose?

Some commonly reported symptoms of an overdose with Depakote include: Drowsiness Heart block (a problem with the electrical system of the heart) Coma Loss of life.

What causes low Depakote levels?

Call your healthcare provider right away if you get any of the following symptoms: nausea or vomiting that does not go away, loss of appetite, pain on the right side of your stomach (abdomen), dark urine, swelling of your face, or yellowing of your skin or the whites of your eyes. Depakote may harm your unborn baby.