What does Selincro do?

Selincro contains the active substance nalmefene. Selincro is used for the reduction of alcohol consumption in adult patients with alcohol dependence who still have a high level of alcohol consumption 2 weeks after the first consultation with their doctor.

How does nalmefene make you feel?

Nalmefene side effects extreme drowsiness; weak or shallow breathing; chest pain or fluttering in your chest; or. feeling like you might pass out.

How long does Selincro last?

Data on the use of Selincro from standard clinical studies are available for a period of six months to one year. Caution is advised if Selincro is prescribed for more than one year. How does Selincro work? The active substance in Selincro, nalmefene, attaches to certain opioid receptors in the brain.

How long does nalmefene stay in system?

The effects of Nalmefene are usually apparent after one to two hours, typically lasting for between twelve and twenty-four hours, although in some instances it can be longer.

How do you get to Selincro?

Can I buy Selincro (nalmefene) online? The Online Clinic can prescribe this medication following a consultation via our website. You will be assessed by one of our GPs. You will need to complete an alcohol diary, and this is made available to you electronically after your quick online consultation.

What is the difference between naltrexone and nalmefene?

Naltrexone and Opioid Antagonists for Alcohol Dependence While nalmefene has a similar chemical structure to naltrexone, it is purported to have improved opioid receptor binding, improved bioavailability, and less of a risk for liver toxicity than naltrexone.

How do you get to selincro?

Is nalmefene the same as naltrexone?

Nalmefene is, similar to naltrexone, an antagonist at the mu- and delta-opioid receptors, but, in contrast to naltrexone, acts also as a partial agonist at the kappa receptor (Bart et al., 2005).

Does naltrexone make you feel weird?

In some people, naltrexone appears to be a kappa agonist—that means it increases the effects of kappa, which means that it has unpleasant effects. Many patients report, when they take naltrexone, that they feel some kind of strange intoxication. They feel weird.

Is naltrexone bad for your liver?

Naltrexone may cause liver damage when taken in large doses. It is not likely that naltrexone will cause liver damage when taken in recommended doses. Tell your doctor if you have or have ever had hepatitis or liver disease.

Can I get naltrexone on the NHS?

In May 2013 a new drug Nalmefene (Selincro) was launched. Naltrexone is also prescribed for alcohol dependence. It is not included here however, as it can also be used to treat drug dependence and the condition that Naltrexone is prescribed to treat is not available within the PACT data.

What are the benefits and side effects of Selincro?

Selincro 1 Therapeutic Indication. Selincro is indicated for the reduction of alcohol consumption in adult… 2 Selincro is medicine that contains the active substance nalmefene. 3 Selincro is used to help reduce alcohol consumption in adults… 4 Before starting treatment with Selincro,…

How many mg of Selincro can you take in a day?

It is available as tablets (18 mg). What is Selincro used for? Selincro is used to help reduce alcohol consumption in adults with alcohol dependence who consume more than 60 g of alcohol per day (for men) or more than 40 g per day (for women).

Is there a way to avoid alcohol with Selincro?

There is no requirement to instantly try and avoid alcohol, in fact the Sinclair Method works by combining the physical effects of Selincro with the individual drinking. Each time alcohol is taken with the drug, the brain is reconditioned slightly not to expect the release of endorphins which create the pleasure.

Is it safe to take Selincro with nalmefene?

Selincro must not be used in people who are hypersensitive (allergic) to nalmefene or any of its other ingredients. It must not be used in patients taking opioid medicines, in patients who have a current or recent addiction to opioids, patients with acute opioid withdrawal symptoms, or in patients suspected to have used opioids recently.