What disease does T4 bacteriophage cause?

The T4 Phage initiates an E. coli infection by recognizing cell surface receptors of the host with its long tail fibers (LTF).

What kind of infection do bacteriophages cause?

In the course of replication and release of the new phage particles, the host bacterium is lysed, and thus killed. Phages that can only carry out this type of infection are called lytic, or virulent, phages. Phages can also carry out a lysogenic infection in which the phage inserts its genome into the bacterial genome.

Does T4 bacteriophage infect bacteria?

The virus bacteriophage T4 infects the bacterium Escherichia coli using an intriguing nanoscale injection machinery that employs a contractile tail. The injection machinery is responsible for recognizing and puncturing the bacterial host and transferring the viral genome into the host during infection.

What is a bacteriophage infection?

A bacteriophage is a type of virus that infects bacteria. In fact, the word “bacteriophage” literally means “bacteria eater,” because bacteriophages destroy their host cells. All bacteriophages are composed of a nucleic acid molecule that is surrounded by a protein structure.

What kind of bacteriophage is Escherichia coli T4?

Jump to navigation Jump to search. Enterobacteria phage T4 is a bacteriophage that infects Escherichia coli bacteria. The T4 phage is a member of the T-even phages, a group including enterobacteriophages T2 and T6. T4 is capable of undergoing only a lytic lifecycle and not the lysogenic lifecycle.

How does morphogenesis take place in the phage T4 virion?

During assembly of the bacteriophage (phage) T4 virion, the morphogenetic proteins encoded by the phage genes interact with each other in a characteristic sequence. Maintaining an appropriate balance in the amounts of each of these proteins produced during viral infection appears to be critical for normal phage T4 morphogenesis.

How does T4 virus infect other bacteria?

T4 infects E. coli. Other phages infect other kinds of bacteria. The phage DNA “hijacks” the bacteria’s cellular machinery, forcing it to produce many new copies of the phage. When the new phage particles have been assembled, they burst out of the bacteria and start the cycle over again. (Wikipedia, 2010.)

How is T4 infection of stationary phase E coli?

Patterns of T4 Infection of E. coli in Stationary Phase: Those infected stationary phase cells that enter hibernation mode are still able to respond with a similarly large burst of phage (about 200 phage per initial cell over 4 h) if the nutrients are not added until 25 h after infection (Figure 1C ).