What causes clear cell acanthoma?

Differential Diagnosis The primary differential diagnoses for clear cell acanthoma include pyogenic granuloma, benign lichenoid keratosis, inflamed seborrheic keratosis, eccrine poroma, basal cell carcinoma, squamous cell carcinoma, amelanotic melanoma, and psoriasis.

What is a clear cell acanthoma?

Clear cell acanthoma is an uncommon type of benign epithelial tumor. Typically, it is a solitary lesion found on the lower limbs. It presents as a nodule or small plaque with slow and well-defined growth.

How common is clear cell acanthoma?

It is currently not known why clear cell acanthoma occurs. Although rare, they occur mostly in adults of middle-age or older. Both male and females can be affected.

Is large cell Acanthoma malignant?

Large cell acanthoma is a relatively uncommon, benign neoplasm considered to be a subtype of solar lentigo or seborrheic keratosis. It typically presents as a scaly, tan macule or thin plaque on photodamaged skin, usually in elderly patients. Large cell acanthomas are characteristically solitary or few in number.

How is Acanthoma treated?

Typical treatment involves removal of the cutaneous irritant. Intralesional triamcinolone may hasten resolution of the lesion, possibly through its potent anti-inflammatory effects in the skin. Surgical removal is usually reserved for cases resistant to treatment or when the diagnosis is in doubt.

What is a clear cell Hidradenoma?

Clear cell hidradenoma is a benign skin appendage tumor that may mimic conventional-type renal cell carcinoma. Histologically, clear cell hidradenoma contains small ductular lumens, focal apocrine and squamoid change, and a less prominent vascular pattern than renal cell carcinoma.

What is a cutaneous horn?

The cutaneous horn appears as a funnel-shaped growth that extends from a red base on the skin. It is composed of compacted keratin (the same protein in nails). The size and shape of the growth can vary considerably, but most are a few millimeters in length. Squamous cell carcinoma is often found at the base.

Should Keratoacanthoma be removed?

It’s not unusual for a single keratoacanthoma to shrink and disappear on its own after several months. But it may leave a worse scar than one from surgery. It could also come back, so it’s best to get it removed. If you don’t treat it, keratoacanthoma can spread throughout your body.

What is a large cell Acanthoma?

The large cell acanthoma presents as a slightly scaly tan macule on photodamaged skin. Clinically, it may be difficult to differentiate from a lentigo senilis, pigmented actinic keratosis, or a flat and pigmented seborrheic keratosis. We have studied 19 cases of large cell acanthoma.

How do you get rid of acanthoma fissuratum?

The principle treatment of acanthoma fissuratum includes removal of the chronic irritating stimulus which usually leads to the reversal of the lesion. Other modalities such as surgical excision, intralesional corticosteroids as well as electrosurgery can be used in persistent cases.

What is the apocrine sweat gland?

A type of gland that is found in the skin, breast, eyelid, and ear. Apocrine glands in the breast secrete fat droplets into breast milk and those in the ear help form earwax. Apocrine glands in the skin and eyelid are sweat glands.