What are the chief cells of the parathyroid?
What are the chief cells of the parathyroid?
Chief cells: The chief cells manage the secretion of parathyroid hormone (PTH). When the cells are viewed, they contain prominent Golgi apparati and a developed endoplasmic reticulum to help with the synthesis and secretion of the hormone.
What is chief cells of stomach?
The gastric chief cell (also known as a zymogenic cell or peptic cell) is a cell in the stomach that releases pepsinogen and chymosin. Pepsinogen is activated into the digestive enzyme pepsin when it comes in contact with hydrochloric acid produced by gastric parietal cells.
What do chief cells in the stomach secrete?
DIGESTION AND ABSORPTION The chief cells secrete pepsinogen, a moderately sized zymogen protein with a molecular weight of 40,400. Pepsin, an enzyme with a molecular weight of 32,700, is formed in the acidic environment of the stomach when pepsinogen loses its activation peptides.
What is the chief cells of parathyroid gland staining?
Parathyroid chief cells (also called parathyroid principal cells or simply parathyroid cells) are one of the two cell types of the parathyroid glands, along with oxyphil cells….
Parathyroid chief cell | |
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Micrograph of a parathyroid gland. H&E stain. | |
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Location | Parathyroid gland |
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What is the main function of the parathyroid gland?
Parathyroid glands produce parathyroid hormone, which plays a key role in the regulation of calcium levels in the blood. Precise calcium levels are important in the human body, since small changes can cause muscle and nerve problems.
What is the parathyroid gland hormone?
Parathyroid hormone regulates calcium levels in the blood, largely by increasing the levels when they are too low. It does this through its actions on the kidneys, bones and intestine: Bones – parathyroid hormone stimulates the release of calcium from large calcium stores in the bones into the bloodstream.
What do G cells do?
G-cells are neuroendocrine cells responsible for the synthesis and secretion of gastrin. They are primarily found in the pyloric antrum but can also be found in the duodenum and the pancreas. They secrete gastrin when stimulated directly by vagal efferent neurons as well as GRP neurons.
What is the pH of the stomach?
The normal volume of the stomach fluid is 20 to 100 mL and the pH is acidic (1.5 to 3.5). These numbers are converted to actual acid production in units of milliequivalents per hour (mEq/hr) in some cases.
Where is the site of chief cells in stomach?
Anatomy. In mammals, chief cells are located at the base of glands distributed throughout the fundus and corpus of the stomach. It is thought that chief cells derive from mucous neck cells located in the midportion of the glands.
What is the structure of the parathyroid?
The parathyroid glands are tiny, round structures usually found embedded in the posterior surface of the thyroid gland (Figure 1). A thick connective tissue capsule separates the glands from the thyroid tissue. Most people have four parathyroid glands, but occasionally there are more in tissues of the neck or chest.
Does parathyroid affect weight?
Parathyroid disease and hyperparathyroidism are associated with weight gain. The worries about gaining weight after parathyroid surgery are understandable but unfounded. It is a myth that parathyroid surgery and removing a parathyroid tumor causes you to gain weight.
What happens if hyperparathyroidism is left untreated?
The effects of hyperparathyroidism can result in other health concerns, if left untreated. In addition to kidney stones and osteoporosis, older patients may physical symptoms including depression, mood changes, fatigue, muscle, and bone aches and pains, or even cardiac dysrhythmias.
What are the chief cells of the parathyroid gland?
Chief cells – The role of this cell type is to secrete parathyroid hormone. They contain prominent Golgi apparatus and endoplasmic reticulum to allow for the synthesis and secretion of parathyroid hormone. The chief cells are the smaller of the two cell types, however they are more abundant.
How is chief cell hyperplasia similar to parathyroid adenoma?
In many way, chief cell hyperplasia is similar to parathyroid adenoma. The hyperplasia is seen as an enlargement of all four of the parathyroid glands, as opposed to a parathyroid adenoma is viewed as an enlargement of one gland.
How is the secretion of parathyroid hormone regulated?
Principal cells predominate and secrete parathyroid hormone, which raises blood calcium levels. Parathyroid hormone secretion is regulated by blood calcium levels. The function of oxyphil cells, the minor cell type, is unclear. 100x The parathyroids consist of two pairs of glands embedded in the posterior surface of the thyroid gland.
How is the capsule of the parathyroid gland invested?
Parathyroid Gland Capsule: Each parathyroid gland is invested with a fibrous capsule that is continuous with the thyroid capsule. Thin extensions of the capsule enter the gland itself and divide each gland into small lobules. These are the primary functional cells of the parathyroid gland.
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