Is RISUG available in the US?

A Berkeley, California-based non-profit called the Parsemus Foundation has licensed the RISUG technology in the US. And the related product they’ve developed, Vasalgel, is only in the preclinical phase of testing. According to Parsemus, the results from animal studies — on rabbits and monkeys — are promising.

Is RISUG approved?

RISUG, developed in India, is another intravasal injectable male contraceptive that can make men sterile for 10 to 15 years. Animal models show that it is completely reversible. Recently, RISUG was approved in India, but as a permanent contraceptive solution and not as a reversible contraceptive.

Is RISUG safe?

RISUG intravasal injection appears to be a safe clinical procedure with no significant adverse effects and has high sustained contraceptive efficacy. The localized intervention and continued contraceptive action on single-dose administration were significant features of the RISUG technology.

When was RISUG invented?

After being introduced in 1980 successful pre-clinical efficacy and safety studies on various species of animals including primates, RISUG® has also been tested successfully in number of human volunteers during Phase-I, Phase-II and Phase-III clinical trials.

Is Vasalgel safe?

Interpretation & conclusions: RISUG intravasal injection appears to be a safe clinical procedure with no significant adverse effects and has high sustained contraceptive efficacy.

Is RISUG reversible?

Over the last two decades RISUG has been drawing attention in the field of male contraception. It promises to sterile men for a period of up to 10-15 years. According to recent studies in animal models, it proves to be completely reversible.

What are the side effects of RISUG?

Reduced side effects – After testing RISUG on more than 250 volunteers, neither Guha nor other researchers in the field report have reported any adverse side effects other than a slight scrotal swelling in some men immediately following the injection which goes away after a few weeks.

Is there a male version of IUD?

But until now, there hasn’t been an equivalent option for men. The only long-term contraceptive for men in the U.S. is the vasectomy, a surgery that’s more invasive than an IUD and far more difficult to undo.

Is Vasalgel reversible?

Vasalgel™ is a high molecular weight polymer consisting of styrene-alt-maleic acid (SMA) dissolved in dimethyl sulfoxide being developed as a reversible male contraceptive device. It forms a hydrogel when implanted into the vasa deferentia, which prevents the passage of sperm.

What are the side effects of Vasalgel?

The side effects of Vasalgel are minimal, it does not have the side effects of a vasectomy and it is not hormonal, therefore it does not have an influence in the body’s hormonal system of men. The noticeable side effect could be a little bit of swelling after the injection, which goes away soon.

Why is RISUG not in use in the United States?

RISUG is a polymer that has been in clinical trials for over 15 years and has now reached the advanced trial stage. Unfortunately, the only men using RISUG are the ones that live close by to the study sites in India since it is not yet on the market. I was very intrigued by this concept. Why was it not in use in the United States?

When did RISUG come out in the US?

In 2010, the Parsemus Fundation purchased the rights to bring RISUG to the American market. Their team is four months into a successful clinical trial on rabbits, and they hope to begin human trials at the end of this year.

What does RISUG stand for in medical category?

RISUG, which stands for Reversible Inhibition of Sperm Under Guidance, is non-hormonal, minimally invasive, reversible, and is effective for up to 10 years. 1  It’s like having a vasectomy—without the permanent snip.

Is there a US patent for RISUG Vasalgel?

It has been patented in India, China, Bangladesh, and the United States. A method based on RISUG, Vasalgel, is currently under development in the US by Parsemus foundation.