How do you administer amiodarone?

Whenever repeated or continuous infusions are intended, administration via a central line is recommended. In extreme clinical emergency, amiodarone may at the discretion of the clinician, be given as a slow injection of 150-300 mg (or 2.5 – 5 mg/kg) in 10-20 ml 5% glucose over a minimum of 3 minutes.

What is the route of amiodarone?

In adult patients, amiodarone can be given for VT/VF cardiac arrest via intravenous (IV)/intraosseous (IO) infusion as a 300 mg rapid bolus followed by an additional bolus of 150 mg IV/IO if VT or VF persists.

Can amiodarone be given IV push?

May administer IV push for ventricular fibrillation or pulseless ventricular tachycardia. The same dosage may be given via the intraosseous route when IV access is not available. 5 mg/kg/dose IV; may repeat dose twice up to 15 mg/kg IV (Max single dose: 300 mg IV).

Can you give amiodarone in normal saline?

Amiodarone is incompatible with saline and should be administered solely in 5% dextrose solution.

What should be avoided when taking amiodarone?

amiodarone food You should avoid consuming grapefruits and grapefruit juice while taking amiodarone. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor. Grapefruit can raise the levels of amiodarone in your body and lead to dangerous side effects.

How do you give amiodarone IV bolus?

Use of a 0.2 or 0.22 micron filter is recommended for intermittent and continuous infusions.

1. Bolus doses: in 100 ml D5W over 10 min (maximum infusion rate 30 mg/min)
2. Continuous infusion: in 500 ml D5W (in non PVC bag) over 24 hours.
3. Cardiac Arrest: First dose: Give 300 mg (6 mL) IV direct UNDILUTED.

What do you flush amiodarone with?

After completion of a risk/benefit analysis, the QAS authorises the administration of sodium chloride 0.9% (flush or running IV line) following amiodarone administration in cardiac arrest, despite manufacturer’s recommendations. Slow push over 2 minutes. Repeated once at 150 mg after 5 minutes.

What solution is amiodarone compatible with?

Amiodarone hydrochloride is stable when mixed with either 5% dextrose injection or 0.9% sodium chloride injection in polyvinyl chloride or polyolefin containers alone or with potassium chloride, lidocaine, procainamide, verapamil, or furosemide and stored for 24 hours at 24 degrees C.

Is amiodarone a last resort?

Although amiodarone is the most effective antiarrhythmic agent for maintaining sinus rhythm in patients with atrial fibrillation, it is generally used as the drug of the last resort in the United States.

What are the five routes of medication administration?

There are five distinct methods for taking a medicine or drug. These methods are: (1) topical administration, (2) inhalation, (3) oral administration, (4) injection, and (5) rectal administration. Topical administration refers to drug that is applied on a surface, such as the skin.

What is the fastest route of Drug Administration?

The route by which the medicines are directly introduced into the bloodstream through a vein is known as intravenous route of administration. The intravenous route is considered to be the fastest route of drug administration.

What are the routes of medication administration?

Route of Administration – the method by which a person takes or receives a drug. The common routes administration are oral (by mouth), sublingual (beneath the tongue), injection, topical, transdermal, and rectal. Women may use some drugs intravaginally.

How to administer amiodarone bolus?

Administer via syringe driver at a rate of 100 mL/hour (over 30 minutes). Maintenance dose – 900 mg over 24 hours. Syringe preparation: Mix 150 mg (3 mL) of amiodarone with 47 mL of glucose 5% in a 50 mL syringe to achieve a final concentration of 3 mg/mL. Ensure all syringes are appropriately labelled.