What is the product of Kolbe Schmitt Kolbe reaction?

It is a carboxylation reaction where sodium phenoxide is heated with carbon dioxide under a pressure of 100 atmospheres and a temperature of 125 degrees Celsius, and the resulting product is treated with sulfuric acid to yield salicylic acid (an aromatic hydroxy acid).

What is Kolbe reaction explain?

1 : the synthesis of a hydrocarbon (as ethane) by the electrolysis of a salt (as sodium acetate) 2 : the synthesis of salicylic acid by heating a mixture of sodium phenoxide and carbon dioxide under pressure at 180° to 200° C.

What is Kolbe reaction with example?

(i) Kolbe’s reaction: When phenol is treated with sodium hydroxide, sodium phenoxide is produced. This sodium phenoxide when treated with carbon dioxide, followed by acidification, undergoes electrophilic substitution to give ortho-hydroxybenzoic acid as the main product. This reaction is known as Kolbe’s reaction.

Which one is the missing reagent of Kolbe Schmitt reaction?

Thus the missing reagent of Kolbe Schmidt reaction is carbon dioxide.

What is the mechanism of the Kolbe-Schmitt reaction?

One of the added CO2moieties performs an electrophilic attack on the benzene ring, whereas the old CO 2moiety becomes a molecule of solvent. Our findings are in good accord with the experimental results obtained by the NMR and IR measurements. called the Kolbe – Schmitt reaction.

How is salicylic acid produced in the Kolbe reaction?

The illustration for the Kolbe reaction mechanism is given below: Thus, the required aromatic hydroxy acid – salicylic acid is produced via the Kolbe reaction. It can be observed that there is a nucleophilic addition of sodium phenoxide to carbon dioxide gas to form the salicylate in the mechanism.

What can be made from the Kolbe reaction?

Kolbe reaction can also be used for the industrial synthesis of 3-hydroxy-2-naphthoic acid, which is a common precursor to azo dyes and pigments. The salicylic acid can be used to make aspirin by reacting it with acetic anhydride. Aspirin is commonly used as a painkiller.

Which is the most efficient route for Kolbe Schmitt synthesis?

On the contrary, for the phloroglucinol a very efficient Kolbe-Schmitt synthesis route could be established using the micro reactor with yields up to 65%.