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What is the most common side effect of theophylline?

What is the most common side effect of theophylline?

Nausea/vomiting, stomach/abdominal pain, headache, trouble sleeping, diarrhea, irritability, restlessness, nervousness, shaking, or increased urination may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.

What are toxic side effects of theophylline?

Complications

  • Arrhythmias.
  • Cardiac arrest.
  • Acute lung injury.
  • Agitation, hallucinations.
  • Seizures.
  • Heart failure.
  • Liver dysfunction.

Is theophylline an agonist or antagonist?

Theophylline is a methylxanthine related to caffeine. It is a β‐adrenergic agonist and exerts its effect through inhibition of phosphodiesterase and induction of catecholamine release.

Is theophylline good for asthma?

Theophylline is used to prevent and treat wheezing, shortness of breath, and chest tightness caused by asthma, chronic bronchitis, emphysema, and other lung diseases. It relaxes and opens air passages in the lungs, making it easier to breathe.

Are there any anti inflammatory effects of theophylline?

More recently it has been shown to have anti-inflammatory effects in asthma and COPD at lower concentrations.

Are there any other salts similar to theophylline?

Other salts, such as choline theophyllinate, do not have any advantage and others, such as acepifylline, are virtually inactive. Doxofylline (7-(1,3-dioxalan-2-yl-methyl) theophylline) has similar efficacy to theophylline but has less effect on adenosine receptors so fewer cardiovascular and central side effects [5].

Which is better for you doxofylline or theophylline?

Doxofylline (7-(1,3-dioxalan-2-yl-methyl) theophylline) has similar efficacy to theophylline but has less effect on adenosine receptors so fewer cardiovascular and central side effects [5]. It is well tolerated when given twice daily by mouth. 3. Molecular Mechanisms of Action

What are the side effects of theophylline overdose?

Overdose can also occur slowly over time if your daily doses are too high. To be sure you are using the correct dose, your blood will need to be tested often. Overdose symptoms may include severe nausea and vomiting, seizure, slow heart rate, weak pulse, or fainting.