What is the molecular cause of cancer?

The p53 gene—named for the molecular mass of its protein product—may be the most important gene in human cancer. This tumor suppressor gene is mutated in about half of all human cancers.

What are three of the molecular causes of cancer?

About genetic mutations

• Acquired mutations. These are the most common cause of cancer.
• Germline mutations. These are less common.
• Tumor suppressor genes. These are protective genes.
• Oncogenes. These turn a healthy cell into a cancerous cell.
• DNA repair genes. These fix mistakes made when DNA is copied.

Is cancer a molecular disease?

Cancer is a rapidly evolving, multifactorial disease that accumulates numerous genetic and epigenetic alterations. This results in wide phenotypic and molecular heterogeneity within the tumor, the complexity of which is further amplified through specific interactions between cancer cells and the tumor microenvironment.

What disease mechanism is cancer?

Cancer is a disease caused when cells divide uncontrollably and spread into surrounding tissues. Cancer is caused by changes to DNA. Most cancer-causing DNA changes occur in sections of DNA called genes. These changes are also called genetic changes.

How are computer scientists working to’solve’cancer?

Fisher takes the computational approach to cancer research. She thinks of it like computer scientists think about computer programs. Her goal is to understand the program, or set of instructions, that causes a cell to execute its commands, or behave in a certain way.

What is Molecular Cancer?

Molecular Cancer is an open access, peer-reviewed journal interested in attracting high-quality original research and reviews that present or highlight significant advances in all areas of cancer and related biomedical science.

Which is the best journal for Molecular Cancer?

Molecular Cancer is a top rated Springer Nature journal. Prof. Christophe Nicot and the editorial team performed in the top percentile of journals based on data collected from the Journal Author Satisfaction Survey.

How can DNA be used to diagnose cancer?

Recent work has revealed that the levels of multiple microRNAs in serum are informative as biomarkers for the diagnosis of cancers. Here, we designed a DNA molecular computation platform for the analysis of miRNA profiles in clinical serum samples.