What is refractory leukemia?

Refractory AML means the leukemia did not respond to treatment. Complete remission has not been reached because the chemotherapy drugs did not kill enough leukemia cells. Both relapsed and refractory AML need more treatment to reach complete remission.

What does refractory AML mean?

What is relapsed/refractory B cell acute lymphoblastic leukemia?

Relapsed, or recurrent, acute lymphocytic leukemia (ALL) means the leukemia has come back after treatment and reaching remission. Treatment for relapsed ALL is usually given for 2–3 years. Refractory disease means the leukemia did not respond to treatment.

What are refractory patients?

(reh-FRAK-tor-ee) In medicine, describes a disease or condition that does not respond to treatment.

Can AML come back after 5 years?

Relapse after 5 years of complete remission (CR) is uncommon in acute myeloid leukemia (AML). Among 2347 patients seen between 1980 and 2008, 1366 achieved CR; 942 relapsed. Eleven (1.16% of all relapses) relapsed after a CR of >5 years.

Can leukemia relapse after bone marrow transplant?

Results: Leukemic relapse after allogeneic BMT is an important cause of treatment failure. The risk of leukemic relapse varies from 20% to 60% depending on the diagnosis and phase of disease.

What is the difference between relapsed and refractory?

Relapsed CLL is the term for disease that responded to therapy but, after 6 or more months, stopped responding. Refractory disease is the term for CLL that does not result in a remission (but may be stable) or disease that gets worse within 6 months of the last treatment.

What are refractory symptoms?

A refractory symptom is one that cannot be adequately controlled despite aggressive efforts to identify a tolerable therapy that does not compromise consciousness (Cherny 1994). A refractory symptom may be subjective and, at times, nonspecific.

What is primary refractory disease?

Primary refractory Hodgkin’s disease may generally be defined as progression of disease during induction treatment or a partial or transient response (< 60 days) to induction therapy. Salvage chemotherapy is inadequate in this patient population; fewer than 10% of patients survive for 10 years or longer.

Can you live 20 years with leukemia?

Chronic lymphocytic leukemia (CLL) can rarely be cured. Still, most people live with the disease for many years. Some people with CLL can live for years without treatment, but over time, most will need to be treated.

What is the chance of recovery from leukemia?

Leukemia is of different types and survival rate also varies accordingly. Acute Lymphoblastic Leukemia (ALL) occurs mostly in children and has a good survival rate of more than 85%. In case of adults, the disease shows a survival rate of just 50%.

Can someone be fully cured from leukemia?

Yes, acute leukemia can be cured. Not everyone will be cured, but the percent of people who are is getting higher all the time. Leukemia is cancer of the white blood cells. The disease usually affects one of the two major types of white blood cells: lymphocytes and granulocytes.

Is there a known treatment and cure for leukemia?

Acute leukemias can often be cured with treatment. Chronic leukemias are unlikely to be cured with treatment, but treatments are often able to control the cancer and manage symptoms. Some people with chronic leukemia may be candidates for stem cell transplantation , which does offer a chance for cure.

What can lead to leukemia?

Leukemia can be caused by many factors, including heredity (genetics), radiation chemical substances such as radioactive and hazardous substances clams, and also because of the virus.