What is avitene drug used for?

Avitene™ Microfibrillar Collagen Hemostat (MCH) and Avitene™ UltraFoam™ sponge are indicated in surgical procedures as an adjunct to hemostasis when control of bleeding by ligature or conventional procedures is ineffective or impractical.

How is avitene applied?

DOSAGE AND ADMINISTRATION: AVITENE™ (MCH) must be applied directly to the source of bleeding. Because of its adhesiveness, it may seal over the exit site of deeper hemorrhage and conceal an underlying hematoma as in penetrating liver wounds.

How do you make avitene?

Preparation of microfibrillar collagen hemostat (Avitene®) suspension. A: A pasty mixture prepared by mixing Avitene® flour with 9 mL of saline filled into a 10-mL syringe connected with another empty syringe using a three-way stopcock. The paste is agitated by pumping motion to turn it into a suspension.

Is avitene a drug?

Avitene (Microfibrillar Collagen Hemostat) is a new absorbable topical hemostatic agent, of which action mechanisms are platelet entrapment and activation of platelet clotting factors.

What is the purpose of hemostatic agents?

Topical hemostatic agents (physical agents, biologically active agents) and tissue adhesives are used as an adjunct or alternative to standard surgical techniques to manage bleeding from surgical surfaces, and are particularly useful for diffuse nonanatomic bleeding, bleeding associated with sensitive structures, and …

Why can drug classifications become confusing?

Drugs used in medicine generally are divided into classes or groups on the basis of their uses, their chemical structures, or their mechanisms of action. These different classification systems can be confusing, since each drug may be included in multiple classes.

What is surgicel powder?

SURGICEL Powder (oxidized regenerated cellulose) is used adjunctively in surgical procedures to assist in the control of capillary, venous, and small arterial. hemorrhage when ligation or other conventional methods of control are impractical or ineffective.

What is Gelfoam?

GELFOAM Sterile Compressed Sponge is a medical device intended for application to bleeding surfaces as a hemostatic. It is a water-insoluble, off-white, nonelastic, porous, pliable product prepared from purified porcine skin, Gelatin USP Granules and Water for Injection, USP.

What are the types of hemostatic agents?

The primary types of hemostatic agents reviewed in this article are dried plasma, fibrinogen concentrate (FC), tranexamic acid, dried and synthetic platelets, and topical hemostatic products currently deployed in combat and prehospital settings (Combat Gauze, HemCon, Celox, XStat).

What are examples of hemostatic agents?

PHARMACOLOGICAL SYSTEMIC HEMOSTATIC AGENTS

• Aprotinin. Aprotinin is a broad-spectrum protease inhibitors, reduces fibrinolysis and stabilizes platelet function.
• Nafamostat Mesilate.
• Tranexamic Acid.
• Epsilon-aminocaproic Acid.
• Vasopressin Analogue: Desmopressin.
• Estrogens.
• Ethamsylate.

What are the 4 types of drug?

What types of drug are there?

• stimulants (e.g. cocaine)
• depressants (e.g. alcohol)
• opium-related painkillers (e.g. heroin)
• hallucinogens (e.g. LSD)