What is an endplate of the spine?

A vertebral end plate is the transition region where a vertebral body and intervertebral disc interface with each other. A vertebral end plate is commonly described as consisting of 2 layers: Cartilaginous layer (also called cartilaginous endplate) that fuses with the disc.

What are end plate changes?

Vertebral endplate (Modic) changes are bone marrow and endplate lesions visible in magnetic resonance imaging (MRI). They are shown to be associated with degenerative intervertebral disc disease [1–3]. Several studies have shown Modic changes as an indicator of symptomatic disc degeneration [13–18].

What is motor end plate?

Neuromuscular junctions, also called motor end plates, are specialised chemical synapses formed at the sites where the terminal branches of the axon of a motor neuron contact a target muscle cell. The axon end knob represents the presynaptic part of the neuromuscular junction.

Does end plate sclerosis cause pain?

Theoretically, due to the histological characteristics of Modic changes, they may cause low back pain. However, it is difficult to distinguish this low back pain from the low back pain caused by disc degeneration in clinical research.

What are the effects of end plate changes?

End plate changes may lead to severe degenerative disc problems that cause life-changing effects, notes Laser Spine Institute. Nonsurgical treatments for degenerative disc conditions include anti-inflammatory medications, pain-relieving drugs, physical therapy and exercise.

What are bone spurs and what are endplates?

Bone spur: It is where the endplate of the vertebral bodies rub, and bone spurs form there. Bone spurs: Endplates are vertebral body structures adjacent to the intervertebral disc. Each vertebra has a superior and inferior endplate, with a few exceptions.

What is the definition of a vertebral end plate?

Spine Anatomy Overview Video A vertebral end plate is the transition region where a vertebral body and intervertebral disc interface with each other. A vertebral end plate is commonly described as consisting of 2 layers: Cartilaginous layer (also called cartilaginous endplate) that fuses with the disc

What causes a discogenic change in the end plate?

Causes of discogenic end plate changes include aging, pressure from a herniated disc, overuse and improper lifting. The vertebrae in the spine are divided by cushioning discs, states Laser Spine Institute. An area of thickened bone called an end plate lies above and below each vertebra.