What happens if you are missing chromosome 9?

Features may affect many parts of the body and may include developmental delay , low muscle tone ( hypotonia ), distinctive facial features, heart conditions, scoliosis , and/or genital abnormalities. Chromosome testing of both parents can provide more information on whether the deletion was inherited .

What is the function of chromosome 9?

Research shows that several genes that control cell growth and division are located on chromosome 9. Many of these genes are tumor suppressors, which means they normally help prevent cells from growing and dividing in an uncontrolled way.

What is 9p syndrome?

Deletion 9p syndrome is a rare structural chromosomal disorder characterized by craniofacial dysmorphism, various congenital malformations, and psychomotor delay.

What are the symptoms of monosomy 9p?

Monosomy 9p is a rare chromosomal anomaly characterized by psychomotor developmental delay, facial dysmorphism (trigonocephaly, midface hypoplasia, upslanting palpebral fissures, dysplastic small ears, flat nasal bridge with anteverted nostrils and long philtrum, micrognathia, choanal atresia, short neck), single …

What is Trisomy 9 called?

Mosaic trisomy 9 is a rare chromosomal disorder in which the entire 9th chromosome appears three times (trisomy) rather than twice in some cells of the body. The term “mosaic” indicates that some cells contain the extra chromosome 9, while others have the typical chromosomal pair.

What’s the difference between trisomy 13 and 18?

Most people have 23 pairs of chromosomes in their cells. Trisomy means that a person has 3 of a certain chromosome instead of 2. Trisomy 13 means the child has 3 copies of chromosome number 13. Trisomy 18 means the child has 3 copies of chromosome number 18.

Is there a cure for monosomy 9p?

Unfortunately there is no cure for 9p Deletion Syndrome, but there are many therapies and medical treatments available to assist families and 9pminus individuals. What’s in a Name? Since 9p deletions are rare and vary according to breakpoints, there is not a single name given to the disorder.

Is there such a thing as chromosome 9 monosomy?

General Discussion. Chromosome 9, Partial Monosomy 9p is a rare chromosomal disorder in which there is deletion (monosomy) of a portion of the 9th chromosome.

How is DNA deleted in Monosomy 9p Syndrome?

Monosomy 9p (also known as Alfi’s Syndrome or simply 9P-) is a rare chromosomal disorder in which some DNA is missing or has been deleted on the short arm region, “p”, of one of the 9th Chromosomes. This deletion either happens de novo or a result of a parent having the chromosome abnormality.

What happens to cells with mosaic trisomy 9?

In people with mosaic trisomy 9, this attempt may be partly successful, leaving some cells with an extra chromosome 9 and some cells with the extra chromosome deleted (the usual chromosome number). This correction process is called trisomy rescue. [1] [2]

What kind of malformations does chromosome 9 have?

Individuals with Chromosome 9, Partial Monosomy 9p may also have various malformations of the hands and feet.