What did Lap-Chee Tsui discover?

cystic fibrosis
Lap-Chee Tsui (1950-) Lap-Chee Tsui is a geneticist who discovered the gene thought to be partly responsible for cystic fibrosis (CF), and his research team sequenced human chromosome 7.

Where did Lap-Chee Tsui go to school?

University of Pittsburgh
The Chinese University of Hong Kong
Lap-Chee Tsui/Education

Who is dr Lap-Chee Tsui?

Lap-Chee Tsui GBM OC OOnt JP FRS FRSC (Chinese: 徐立之; pinyin: Xú Lìzhī; Jyutping: ceoi4 laap6 zi1; born 21 December 1950) is a Chinese-born Canadian geneticist and served as the 14th Vice-Chancellor and President of the University of Hong Kong.

When did Dr Lap-Chee Tsui immigrate to Canada?

January 1981
I came to Canada in January 1981 to join Manual Buchwald and Jack Riordan’s lab to try to figure out the basic defect in cystic fibrosis (CF), a fatal genetic disease affecting quite a large part of the Canadian population.

Why did Dr Lap Chee Tsui come to Canada?

Tsui, Lap-Chee In 1982 he was recruited by a Massachusetts-based biotechnology firm, Collaborative Research, to investigate the genetic cause of cystic fibrosis at HSC’s cystic fibrosis clinic at Toronto. Together, they identified the gene-bearing chromosome responsible for CF.

What chromosome is the CFTR gene on?

The gene that encodes the CFTR protein, which is also called CFTR, is located on chromosome 7. Mutations in this gene lead to CF.

What gender is most affected by cystic fibrosis?

How Are Men Affected by Cystic Fibrosis? Males account for slightly more than 50 percent of all cases of cystic fibrosis (CF) but generally have better outcomes than females until about age 20. After that, men and women experience roughly equal outcomes for long-term survival.

How can a child inherit cystic fibrosis if neither parent has the disease?

A child can inherit CF only if both parents carry a CF gene (that is, each parent either has CF or is a carrier) and both parents pass the CF gene on to their child. There is nothing that parents do to cause CF in their child and usually they do not know that they are carriers of a CF gene.

What are 5 symptoms of cystic fibrosis?

Symptoms of CF

• Very salty-tasting skin.
• Persistent coughing, at times with phlegm.
• Frequent lung infections including pneumonia or bronchitis.
• Wheezing or shortness of breath.
• Poor growth or weight gain in spite of a good appetite.
• Frequent greasy, bulky stools or difficulty with bowel movements.
• Male infertility.

Are males with CF infertile?

Most men with CF (97-98 percent) are infertile because of an absence of the sperm canal, known as congenital bilateral absence of the vas deferens (CBAVD). The sperm never make it into the semen, making it impossible for them to reach and fertilize an egg through intercourse.

Can a person with CF have a baby?

When you have cystic fibrosis, it’s still possible to get pregnant and carry a baby to term. However, you’ll need to be monitored closely during these nine months to ensure that both you and your little one stay healthy.

What are four symptoms of cystic fibrosis?

What Are the Symptoms of Cystic Fibrosis?

• Chronic coughing (dry or coughing up mucus)
• Recurring chest colds.
• Wheezing or shortness of breath.
• Frequent sinus infections.
• Very salty-tasting skin.

Where did Lap chee Tsui go to college?

He studied Biology at the New Asia College of the Chinese University of Hong Kong and was awarded a B.Sc. (3rd Class Honours) and a M.Phil. in 1972 and 1974, respectively. Upon the recommendation of his mentor at the CUHK, he continued his graduate education in the United States and received his Ph.D. from the University of Pittsburgh in 1979.

When did Lap chee Tsui become Justice of the peace?

Dr Tsui was appointed Justice of the Peace in 2001, and was awarded the Gold Bauhinia Star and the Grand Bauhinia Medal by the Hong Kong SAR Government in 2011 and 2016 respectively. Eminent Scientist, Genome Science Laboratory, Tsukuba Life Science Center, The Institute of Physical and Chemical Research (RIKEN).

What did Lap chee Tsui do for cystic fibrosis?

As the location of the gene associated with cystic fibrosis is now known, it is possible for doctors and specialists to identify in human fetuses the mutation to the gene that partly causes the disease. Tsui’s research also outlined the mechanisms for the development of cystic fibrosis, which were previously unknown.

Where does the last name Tsui come from?

This is a Chinese name; the family name is Tsui. Lap-Chee Tsui, FRS, GBM, OC, O.Ont, JP ( Chinese: 徐立之; pinyin: Xú Lìzhī; Jyutping: ceoi4 laap6 zi1; born 21 December 1950) is a Chinese-born Canadian geneticist and served as the 14th Vice-Chancellor and President of the University of Hong Kong . Tsui was born in Shanghai.